DC10713S-methyl-KE-298
S-methyl-KE-298 is an active metabolite of KE-298. KE-298 inhibits matrix metalloproteinase (MMP-1) production from rheumatoid arthritis (RA) synovial cells.
View activity & pricesDC Chemicals · Research reagentsDC10713 
DCW-016
DC28845
DC70723
DC32472
DCAPI1345
DC9149
DC9605
DCY-106
DC52032
DC2079
DC39810
DCAPI1084
DC53053
DC8013
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DC9475
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DC9249
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DC10830
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Small Molecule Research Tools
2816 products · Page 54 of 59
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DC10713DCW-016Vitamin A
For the detailed information of Vitamin A, the solubility of Vitamin A in water, the solubility of Vitamin A in DMSO, the solubility of Vitamin A in PBS buffer, the animal experiment（test） (test) of Vitamin A, the cell…
View activity & pricesDC28845N-Desmethyl Pimavanserin
N-Desmethyl Pimavanserin is the active metabolite of Pimavanserin. Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC50 and pKd of 8.73 and 9.3, respectively.
View activity & pricesDC70723QC-01–175
QC-01-175 is a hetero-bifunctional molecule designed to engage both tau and Cereblon (CRBN) to trigger tau ubiquitination and proteasomal degradation (tau PROTAC).QC-01–175 effected clearance of tau in frontotemporal…
View activity & pricesDC32472Zinc Pyrithione
Zinc Pyrithione is a dimer of two pyrithione molecules bound by zinc. It is commonly found as an ingredient of commercial anti-dandruff shampoos. This products acts as an antifungal and antibacterial.
View activity & pricesDCAPI1345Ozagrel HCl
For the detailed information of Ozagrel HCl, the solubility of Ozagrel HCl in water, the solubility of Ozagrel HCl in DMSO, the solubility of Ozagrel HCl in PBS buffer, the animal experiment（test） (test) of Ozagrel…
View activity & pricesDC9149Methotrexate
Methotrexate(WR19039; CL14377) can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.in vitro: In normal T cells,…
View activity & pricesDC9605Dienogest
Dienogest(STS-557) is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis. Dienogest is an orally active synthetic progesterone (or progestin).…
View activity & pricesDCY-106Rhoifolin
For the detailed information about the solubility of Rhoifolin in water, the solubility of Rhoifolin in DMSO, the solubility of Rhoifolin in PBS buffer, the animal experiment（test） of Rhoifolin,the in vivo,in vitro and…
View activity & pricesDC52032Luteolin
Luteolin is a falconoid compound, which exhibits anticancer properties.IC50 value:Target: A natural for anticancer.
View activity & pricesDC2079GW-9662
GW9662 is a potent and selective PPARγ antagonist with an IC50 of 3.3 nM, showing 10 and 1000-fold selectivity over PPARα and PPARδ, respectively.
View activity & pricesDC39810ICCB-19
ICCB-19 inhibits RIPK1-dependent apoptosis (RDA) with IC50 of 2.01 μM.
View activity & pricesDCAPI1084Ezetimibe (Zetia)
Ezetimibe (SCH 58235) is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator. Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor.
View activity & pricesDC53053LGD-3303
LGD-3303 is a selective androgen receptor modulator (SARM).
View activity & pricesDC8013CASIN
CASIN is a selective GTPase Cdc42 inhibitor with IC50 of 2 uM.
View activity & pricesDCAPI1200Estradiol
For the detailed information of Estradiol, the solubility of Estradiol in water, the solubility of Estradiol in DMSO, the solubility of Estradiol in PBS buffer, the animal experiment（test） (test) of Estradiol, the cell…
View activity & pricesDC67996SB405483
SB-405483 is a specific small-molecule chemical compound used in scientific research as an allosteric ligand for the protein cereblon (CRBN). It is primarily a biochemical tool for studying protein degradation pathways…
View activity & pricesDC8985Riluzole
Riluzole is an anticonvulsant drug and belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.
View activity & pricesDCAPI1398Disulfiram (Antabuse)
Disulfiram is a specific inhibitor of?aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol.
View activity & pricesDCY-021Folic acid
Folic acid(Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.
View activity & pricesDC9475Ritonavir
Ritonavir is an inhibitor of HIV protease used to treat HIV infection and AIDS.
View activity & pricesDC10707DL-AP4
DL-AP4 (2-Amino-4-phosphonobutyric acid) is a glutamate antagonist. DL-AP4 behaves as a competitive inhibitor of glutamate binding with an apparent Kd of 66 μM. DL-AP4 can be used for the research of central nervous…
View activity & pricesDC9175Fexofenadine Hydrochloride
Fexofenadine is a third-generation antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria.
View activity & pricesDC11325RN-1734
RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50values for all three species (hTRPV4: IC50 = 2.3 μM, mTRPV4: IC50 =…
View activity & pricesDC9003Triamterene
Triamterene blocks epithelial Na+ channel (ENaC) in a voltage-dependent manner, which used as a mild diuretic.Triamterene blocked rENaC in a voltage-dependent manner, and was 100-fold less potent than amiloride at pH…
View activity & pricesDC92493-Cyano-7-ethoxycoumarin
3-Cyano-7-ethoxycoumarin is a fluorescent P450 substrate (excitation/emission wavelengths = 408/455 nm); metabolized to cyano-hydroxycoumarin.
View activity & pricesDC23858Lanraplenib (GS-9876)
Lanraplenib (GS-9876) is a highly selective and oral SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib (GS-9876) inhibits SYK activity in platelets via the glycoprotein…
View activity & pricesDC33129EV-06(Alpha-Lipoic Acid Choline Ester,)
Alpha-Lipoic Acid Choline Ester, also known as alpha-LACE, EV-06 or UNR844, is a drug candidate potentially for the treatment of presbyopia. Alpha-LACE was designed to permeate biological membranes with the…
View activity & pricesDCAPI1581Raltegravir
Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection.
View activity & pricesDC10830IDH-889
IDH889 is an orally available, brain penetrant, allosteric and mutant specific inhibitor of isocitrate dehydrogenase 1 (IDH1). IDH889 has potent selectivity for IDH1 R132* mutations, with IC50s of 0.02 μM, 0.072 μM and…
View activity & pricesDC89536-TG/Thioguanine
6-Thioguanine is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM…
View activity & pricesDC9497VU0152100
VU0152100 is a potent and selective allosteric potentiator of M4 mAChR with an EC50 of 380 ± 93 nM.
View activity & pricesDC73483-Methyladenine
3-Methyladenine is a PI3K inhibitor. 3-Methyladenine is a widely used inhibitor of autophagy via its inhibitory effect on class III PI3K.
View activity & pricesDC20178Pyrrolidinedithiocarbamate ammonium;APDC, PDTC
Pyrrolidinedithiocarbamate ammonium is a selective NF-κB inhibitor.
View activity & pricesDC9837Larotrectinib (LOXO-101 sulfate)
Larotrectinib (LOXO-101) sulfate is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms…
View activity & pricesDC10213Fatostatin
Fatostatin hydrobromide (125B11 hydrobromide), a specific inhibitor of SREBP activation, impairs the activation of SREBP-1 and SREBP-2. Fatostatin hydrobromide binds to SCAP (SREBP cleavage-activating protein), and…
View activity & pricesDC10620CY-09
CY-09 is an NLRP3 inhibitor.
View activity & pricesDC21101BDCRB
BDCRB (GW 275175) is a potent and selective inhibitor of human CMV replication by blocking the processing and maturation of viral DNA.
View activity & pricesDC7112FK 3311
FK 3311 is a selective inhibitor of COX-2; antiinflammatory agent.IC50 Value: 1.6 uM [1]Target: COX-2Cyclooxygenase (COX) is an intracellular enzyme that converts arachidonic acid into prostaglandin (PG)G2 and PGH2.in…
View activity & pricesDC11052GAK inhibitor 12r
GAK inhibitor 12r is a higghly potent, selective inhibitor of cyclin G-associated kinase (GAK) with Kd of 89 nM; targets only 8 other kinases with greater than 90% inhibition in a diverse panel of 468 kinases;…
View activity & pricesDC20280TrkA inhibitor compound 23（TrkA-IN-23）
TrkA-IN-23 is a highly potent, subtype selective, peripherally restricted, allosteric TrkA inhibitor with IC50 of 10 nM, 180-fold selective over TrkB and 70-fold selective over TrkC in cell based assays; exhibits…
View activity & pricesDC74438NRPa-308
NRPa-308 is a neuropilin-1 (NRP-1) antagonist, inhibits the VEGF-A165/NRP-1 binding with IC50 of 42 uM, exerts in vitro anti-angiogenic activity.
View activity & pricesDC57071HB007
HB007 is a small ubiquitin-related modifier 1 (SUMO1) degrader. HB007 induces ubiquitination and degradation of SUMO1, resulting in reduced tumor growth in vivo. HB007 can be used for the research of brain, breast,…
View activity & pricesDC4154Capecitabine
Capecitabine is an oral prodrug that is converted to its active metabolite, fluorouracil (FU), by thymidine phosphorylase.
View activity & pricesDC57111UNC6934
UNC6934 is a potent and selective drug-like chemical probe to interrogate the function of NSD2-PWWP1 with Kd of 91 nM.UNC6934 disrupts the NSD2-PWWP1 interaction with H3K36me2 nucleosomes in U2OS cells as measured by a…
View activity & pricesDC23147Brigatinib (AP-26113)
Brigatinib is a highly potent and selective ALK inhibitor, with an IC50 of 0.6 nM.
View activity & pricesDC32456Pyrinuron
Pyrinuron is an inhibitor of NAMPT and NMNAT2.Pyrinuron is used as a model compound in studies of urea derivatives and their reactivity.Research has explored the effects of this compound on insulin-producing beta…
View activity & pricesDC2100Dasatinib (BMS-354825)
Description of Dasatinib: Dasatinib is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib binds to and inhibits the growth-promoting activities of these kinases.…
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