Steatohepatitis

7 products · Page 1 of 1

All small molecule research tools

DC9995

MGL-3196(Resmetirom)

MGL-3196 is a highly selective thyroid hormone receptor β (THR-β) agonist with an EC50 value of 0.21 μM.

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DC10868

Cilofexor

Cilofexor is a farnesoid X receptor (FXR) agonist.

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DC10173

Firsocostat(ND-630,GS-0976)

Firsocostat (ND-630; GS-0976; NDI-010976) is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively.

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DC9873

Selonsertib（GS-4997）

Selonsertib is an apoptosis signal-regulating kinase 1 (ASK1) inhibitor with a pIC50 of 8.3±0.07.

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DC9762

Emricasan

Emricasan (PF 03491390) is an irreversible pan-caspase inhibitor.

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DC10737

Tropifexor (LJN452)

Tropifexor is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.

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DC8390

Oltipraz

Oltipraz has an inhibitory effect on HIF-1α activation by insulin in a time-dependent manner, completely abrogating HIF-1α induction at ≥10 μM concentrations, the IC50 of Oltipraz for HIF-1α inhibition is 10 μM.

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