Explore 56 research products with specifications, prices and referenced biological activity.
DC10486NCT-503 is a PHGDH inhibitor for studying serine synthesis, one-carbon metabolism and metabolic dependencies in cancer models. Published studies distinguish biochemical inhibition from cellular growth effects and document context-dependent off-target activity.
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DC10881WM-1119 is a KAT6A/KAT6B inhibitor for epigenetic and cellular-senescence research. The primary study reports binding selectivity, lymphoma-cell growth inhibition and suppression of lymphoma progression in mice.
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DC20332CD38 inhibitor 78c is a reversible CD38 NADase inhibitor for NAD+ metabolism and aging research. Published work links CD38 inhibition to cellular NAD+ elevation and functional changes in mouse aging models.
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DC10334ARV-771 is a VHL-recruiting BET protein degrader for prostate cancer and targeted protein degradation research. The primary study reports pan-BET degradation, downstream c-MYC suppression and activity in prostate cancer models.
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DC10880WM-8014 is a KAT6A/KAT6B inhibitor for chromatin, cellular senescence and cancer research. Published work separates biochemical inhibition, fibroblast growth arrest and responses in a zebrafish liver cancer model.
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DC11276KPT-6566 is a covalent PIN1 inhibitor for cancer signaling research. Published studies connect PIN1 inhibition with oxidative stress, DNA damage, cancer-cell death and reduced lung colonization in mice.
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DC1009Laropiprant is a DP1 receptor antagonist for prostanoid signaling and platelet-function research. Its effects on platelet activation vary with agonist and concentration.
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DC10134Obicetrapib, also known as TA-8995, is a CETP inhibitor for lipoprotein metabolism and cholesterol-efflux research.
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DC10168Anle138b is an aggregation-modulating research compound studied in α-synucleinopathies. Published mouse data connect reduced oligomer burden with neuronal and motor outcomes.
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DC1023CHIR-99021 (CT99021) is a GSK-3 inhibitor used in signaling, cell-state and metabolic research.
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DC1028Y-27632 dihydrochloride is a ROCK inhibitor for cell-survival and cytoskeletal research, including dissociated human pluripotent stem-cell cultures.
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DC10280BD1063 dihydrochloride is a sigma-1 receptor antagonist used to study nociplastic pain and glial responses.
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DC1032KY02111 is a small molecule for cardiomyocyte differentiation research in human pluripotent stem cells.
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DC10491CD437 is a retinoid-like research compound with direct DNA polymerase α inhibition and antiproliferative activity in cancer-cell models.
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DC10536KML-29 is a selective MAGL inhibitor used to investigate endocannabinoid metabolism, inflammatory pain and neuropathic pain.
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DC10538IDH-305 (IDH305) is an allosteric mutant-IDH1 inhibitor for studies of 2-hydroxyglutarate production and IDH1-mutant cancer biology.
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DC10607JTE-013 is an S1PR2 antagonist used in sphingosine-1-phosphate signaling, mitochondrial dynamics and fibrosis research.
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DC10719RGX-104 is an LXR agonist for studying myeloid-derived suppressor cells, ApoE signaling and tumor immune responses.
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DC10721Gefapixant (AF-219, MK-7264) is a P2X3 antagonist for ATP-gated ion-channel and sensory signaling research.
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DC10727Elafibranor (GFT505) is a dual PPARα/δ agonist used in hepatic lipid metabolism, inflammation and fibrosis research.
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DC10794PH-002 is an ApoE4 structure-correcting research compound studied in human iPSC-derived neurons with Alzheimer-related phenotypes.
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DC10923TAK-615 is an LPA1 negative allosteric modulator for receptor signaling and fibrosis-related pathway research.
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DC10940MC3343 is a nonnucleoside DNMT inhibitor for epigenetic reprogramming, osteoblastic differentiation and osteosarcoma research.
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DC10965SW076956 is an early BCL-2/Beclin 1 interaction inhibitor used in autophagy-modulation research.
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DC10978BAY-3827 is an AMPK inhibitor with additional RSK-family activity, used to study metabolic signaling and androgen-dependent prostate cancer.
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DC10984ζ-Stat (ZETA-STAT) is a research inhibitor investigated in atypical PKC signaling and invasive behavior of clear-cell ovarian cancer cells.
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DC10988LTX-401 is an amphipathic amino-acid derivative for cytolytic cell-death and local tumor-immunology research.
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DC11043Omidenepag is an EP2 receptor agonist for prostanoid signaling and ocular-cell research.
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DC11047MRL871 (MRL-871) is an allosteric RORγt ligand used in nuclear-receptor research. Independent work also identified PPARγ partial agonism.
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DC1107PF-543 is a potent, sphingosine-competitive SPHK1 inhibitor for investigating S1P production and sphingolipid signaling.
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DC11101Soticlestat is a cholesterol 24-hydroxylase inhibitor used in cholesterol turnover and neuronal-excitability research.
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DC11103Tavapadon (PF-06649751) is a non-catechol D1/D5 partial agonist for dopamine-receptor and motor-function research.
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DC11256OTS193320 is a SUV39H2 methyltransferase inhibitor for histone methylation, DNA-damage-response and cancer-cell research.
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DC11257OTS186935 is a SUV39H2 inhibitor with published cellular and xenograft activity, used in histone-methylation and cancer research.
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DC11299ABC 1183 (ABC1183) is a dual GSK-3/CDK9 inhibitor for cancer-cell proliferation and inflammatory signaling research.
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DC11391KL-1 is a small-molecule disruptor of the super elongation complex for transcriptional elongation and MYC-dependent cancer research.
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DC11392KL-2 is a small-molecule disruptor of the super elongation complex for transcriptional elongation and MYC-dependent cancer research.
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DC11464DO-264 (DO264) is an ABHD12 inhibitor for lysophosphatidylserine metabolism and immune-lipid signaling research.
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DC11475CK-869 is an Arp2/3 complex inhibitor for branched-actin and cytoskeletal research, with reported microtubule-related off-target effects.
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DC11507CLP257 is a neuronal chloride-signaling research compound originally reported as a KCC2 enhancer. Subsequent work challenged direct KCC2 activation and reported GABAA receptor potentiation.
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DC11524Mavacamten (MYK-461) is a cardiac myosin inhibitor used to study sarcomere contractility and hypertrophic cardiomyopathy.
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DC11526Praliciguat is an sGC stimulator for nitric-oxide/cGMP signaling, renal inflammation and fibrosis research.
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DC11530Tapinarof (Benvitimod, GSK2894512) is an AHR-modulating compound for skin inflammation and keratinocyte research.
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DC11658Diptoindonesin G is an HSP90 modulator for chaperone biology and endocrine-resistant breast-cancer research.
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DC11669CB-002 (CB002) is a p53-pathway-restoring research compound studied in colorectal cancer cells and apoptosis signaling.
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DC118279-ING-41 (Elraglusib) is a cancer-research compound originally developed as a GSK-3β inhibitor. Published work documents model-dependent growth inhibition and additional mechanisms.
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DC11954JP-153 is a focal-adhesion-signaling modulator for VEGF-dependent retinal endothelial-cell and angiogenesis research.
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DC12020MK-8722 is a direct allosteric activator of mammalian AMPK complexes for metabolic signaling and glucose-homeostasis research.
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DC12287Delta-valerobetaine is a microbiome-derived metabolite used to investigate mitochondrial fatty-acid oxidation and diet-dependent obesity.
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DC12312OTX008 (Calixarene 0118, PTX008) is a galectin-1 inhibitor used in tumor-cell signaling and viability research.
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DC12391BL-AD008 is an AMPK/ZIPK-directed activator investigated in cervical-cancer apoptosis research.
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DC12396CR4056 is an imidazoline-I2 ligand for pain signaling and monoaminergic research.
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DC12438AG1 is a small-molecule G6PD activator for enzyme oligomerization, NADPH metabolism and redox research.
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DC12482PTC299 (Emvododstat) is a DHODH inhibitor for pyrimidine metabolism and hematological-cancer research.
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DC53131Sulfopin is a covalent PIN1 inhibitor used to study prolyl-isomerase signaling and MYC-driven cancer biology.
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DC53045STM2457 is a catalytic METTL3 inhibitor for RNA methylation, leukemia-cell differentiation and cancer research.
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