Cancer Signaling

CD437 is a retinoid-like research compound with direct DNA polymerase α inhibition and antiproliferative activity in cancer-cell models.

ζ-Stat (ZETA-STAT) is a research inhibitor investigated in atypical PKC signaling and invasive behavior of clear-cell ovarian cancer cells.

LTX-401 is an amphipathic amino-acid derivative for cytolytic cell-death and local tumor-immunology research.

ABC 1183 (ABC1183) is a dual GSK-3/CDK9 inhibitor for cancer-cell proliferation and inflammatory signaling research.

CK-869 is an Arp2/3 complex inhibitor for branched-actin and cytoskeletal research, with reported microtubule-related off-target effects.

Diptoindonesin G is an HSP90 modulator for chaperone biology and endocrine-resistant breast-cancer research.

CB-002 (CB002) is a p53-pathway-restoring research compound studied in colorectal cancer cells and apoptosis signaling.

9-ING-41 (Elraglusib) is a cancer-research compound originally developed as a GSK-3β inhibitor. Published work documents model-dependent growth inhibition and additional mechanisms.

JP-153 is a focal-adhesion-signaling modulator for VEGF-dependent retinal endothelial-cell and angiogenesis research.

OTX008 (Calixarene 0118, PTX008) is a galectin-1 inhibitor used in tumor-cell signaling and viability research.

BL-AD008 is an AMPK/ZIPK-directed activator investigated in cervical-cancer apoptosis research.