5 research products
DC10486NCT-503 is a PHGDH inhibitor for studying serine synthesis, one-carbon metabolism and metabolic dependencies in cancer models. Published studies distinguish biochemical inhibition from cellular growth effects and document context-dependent off-target activity.
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DC10538IDH-305 (IDH305) is an allosteric mutant-IDH1 inhibitor for studies of 2-hydroxyglutarate production and IDH1-mutant cancer biology.
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DC10978BAY-3827 is an AMPK inhibitor with additional RSK-family activity, used to study metabolic signaling and androgen-dependent prostate cancer.
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DC1107PF-543 is a potent, sphingosine-competitive SPHK1 inhibitor for investigating S1P production and sphingolipid signaling.
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DC12482PTC299 (Emvododstat) is a DHODH inhibitor for pyrimidine metabolism and hematological-cancer research.
View activity & pricesNCT-503 is a PHGDH inhibitor for studying serine synthesis, one-carbon metabolism and metabolic dependencies in cancer models. Published studies distinguish biochemical inhibition from cellular growth effects and document context-dependent off-target activity.
IDH-305 (IDH305) is an allosteric mutant-IDH1 inhibitor for studies of 2-hydroxyglutarate production and IDH1-mutant cancer biology.
BAY-3827 is an AMPK inhibitor with additional RSK-family activity, used to study metabolic signaling and androgen-dependent prostate cancer.
PF-543 is a potent, sphingosine-competitive SPHK1 inhibitor for investigating S1P production and sphingolipid signaling.
PTC299 (Emvododstat) is a DHODH inhibitor for pyrimidine metabolism and hematological-cancer research.