DC Chemicals · Research reagents

Cathepsin

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Balicatib chemical structureDC7371

Balicatib

Balicatib(AAE-581) is a potent and selective inhibitor of cathepsin K; 10-100 fold more potent in cell-based enzyme occupancy assays than against cathepsin B, L, and S.

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L-006,235 chemical structureDC7934

L-006,235

L-006,235 is a potent, reversible cathepsin K inhibitor (IC50 = 0.25 nM) that displays > 4000-fold selectivity over cathepsins B, L and S. Displays reduced selectivity in cell-based assays possibly due to lysosomal…

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CA-074-Me chemical structureDC7697

CA-074-Me

CA-074 methyl ester is a specific inhibitor of Cathepsin B, which has potent bioactivities such as neuroprotective, anti-cancer, and anti-inflamatory effects.

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Leupeptin hemisulfate chemical structureDC8688

Leupeptin hemisulfate

Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor, which has been shown to inhibit cathepsins B, H, L, and S, calpain, and trypsin. Leupeptin hemisulfate is an orally active,…

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