Leupeptin hemisulfate chemical structure
Chemical structureResearch use only
CAT. NO. DC8688Featured

Leupeptin hemisulfate

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TotalUS$400
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Product overview

Description & Application

Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor, which has been shown to inhibit cathepsins B, H, L, and S, calpain, and trypsin. Leupeptin hemisulfate is an orally active, antioxidant and anti-inflammatory agent.

ParameterValue
Chemical Name(S)-2-acetamido-N-((S)-1-amino-4-methyl-1-oxopentan-2-yl)-N-((S)-5-guanidino-1-oxopentan-2-yl)-4-methylpentanamide hemisulfate
CAS No.103476-89-7
SynonymsLeupeptin hemisulfate anhydrous; NK-381; NK 381; NK381;
FormulaC40H78N12O12S
M.Wt951.19
SMILESOS(=O)(O)=O.N/C(=N/CCCC(NC(C(NC(C(NC(=O)C)CC(C)C)=O)CC(C)C)=O)C=O)/N.N/C(=N/CCCC(NC(C(NC(C(NC(=O)C)CC(C)C)=O)CC(C)C)=O)C=O)/N
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor, which has been shown to inhibit cathepsins B, H, L, and S, calpain, and trypsin. Leupeptin hemisulfate is an orally active, antioxidant and anti-inflammatory agent.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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