ADC Cytotoxin

6 products · Page 1 of 1

All small molecule research tools

DC7021

Monomethyl auristatin E (vedotin)

Monomethyl auristatin E (MMAE) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug…

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DC7069

Daunorubicin HCL

Daunorubicin hydrochloride is a topoisomerase II inhibitor with potent antineoplastic activities.

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DC57041

N-​Me-​L-​Ala-​maytansinol

N-Me-L-Ala-maytansinol is a hydrophobic, cell permeable payload used for making antibody-drug conjugate (ADC)[1].

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DC8540

DM-1(Mertansine)

Mertansine (DM1) is a microtubulin inhibitor which binds at the tips of microtubules and suppresses the dynamicity of microtubules.. Mertansine is an antibody-conjugatable maytansinoid that was developed to overcome…

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DC28020

Maytansine

Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations[1].

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DC7648

PNU159682

PNU-159682, a highly potent metabolite of the anthracycline nemorubicin with outstanding cytotoxicity, is a potent ADCs cytotoxin.

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