DC7931UNC2025
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.UNC2025 was capable of inhibiting Mer phosphorylation in vivo, following oral dosing as demonstrated by…
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DC7931UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.UNC2025 was capable of inhibiting Mer phosphorylation in vivo, following oral dosing as demonstrated by…
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DC10127UNC569 is a novel small-molecule MER inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo.
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DC10337CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively.
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DC8223TP-0903 is a potent and selective Axl receptor tyrosine kinase inhibitor with an IC50 value of 27 nM.
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