FLT3

6 products · Page 1 of 1

All small molecule research tools

DC5159

CP-868596 (Crenolanib)

Crenolanib is a potent and selective inhibitor of wild-type and mutant isoforms of the class III receptor tyrosine kinases FLT3 and PDGFRα/β with Kds of 2.1 nM/3.2 nM, 0.74 nM, respectively.

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DC5197

Quizartinib (AC220)

Quizartinib (AC220) is a potent Flt3 tyrosine kinase inhibitor with a Kd of 1.6±0.7 nM.

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DC8522

KW-2449

KW-2449 is a multi-targeted kinase inhibitor of FLT3, ABL, ABLT315I and Aurora kinase with IC50s of 6.6, 14, 4 and 48 nM, respectively.

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DC9286

K03861

K03861 is a type II CDK2 inhibitor with Kd of 8.2 nM.K03861 inhibits CDK2 activity by competing with binding of activating cyclins.

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DC7792

G-749

G-749 is a novel FLT3 inhibitor that showed potent and sustained inhibition of the FLT3 wild type and mutants with IC50s of 0.4/0.6/3.5/7.5 nM for Wt Flt3/D835Y/MV4-11/Molm-14 respectively.G-749 showed potent and…

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DC8164

Gilteritinib(ASP2215)

Gilteritinib is a potent FLT3/AXL inhibitor with IC50s of 0.29 nM/0.73 nM, respectively.

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