DCAPI1434Romidepsin（FK-228）
Romidepsin is a potent HDAC1 and HDAC2 inhibitor with IC50s of 36 and 47 nM, respectively.
View activity & pricesDC Chemicals · Research reagentsDCAPI1434 
DC8036
DC3110
DC7548
DC7183
DC7082
DC7978
DC7037
DC5128
DC7284
DC7716
DC7176
DC8134
DC7544
DC9715
DC8252
DC7263
DC7196
DC8350
DC5178
DC8654
DC8663
DC7738
DC8660
DC7962
DC7048
DC4241
DC7280
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DC6909
DC70821
DC2060
DC8646
DC7796
DC7182
DC70478
DC10210
DC6304
HDAC
38 products · Page 1 of 1
All small molecule research tools
DCAPI1434DC8036CAY10603
CAY10603 is a potent and selective HDAC6 inhibitor, with an IC50 of 2 pM; CAY10603 also inhibits HDAC1, HDAC2, HDAC3, HDAC8, HDAC10, with IC50s of 271, 252, 0.42, 6851, 90.7 nM.
View activity & pricesDC3110CUDC-907 (PI3K/HDAC InhibitorI)
Fimepinostat (CUDC-907) potently inhibits class I PI3Ks as well as classes I and II HDAC enzymes with an IC50 of 19/54/39 nM and 1.7/5.0/1.8/2.8 nM for PI3Kα/PI3Kβ/PI3Kδ and HDAC1/HDAC2/HDAC3/HDAC10 , respectively.
View activity & pricesDC7548Nexturastat A
Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM; no inhibition on other HDAC forms.Nexturastat A displayed low micromolar activity compared to the low nanomolar activity against HDAC6.…
View activity & pricesDC7183Panobinostat(LBH589)
Panobinostat is a non-selective histone deacetylase (HDAC) inhibitor.
View activity & pricesDC7082Belinostat (PXD101)
Belinostat inhibits the growth of tumor cells (A2780, HCT116, HT29, WIL, CALU-3, MCF7, PC3 and HS852) with IC50 from 0.2-0.66 μM. PD101 shows low activity in A2780/cp70 and 2780AD cells, which are cisplatin and…
View activity & pricesDC7978Tucidinostat(Chidamide)
Chidamide is a synthetic benzamide-type HDAC inhibitor, inhibits HDAC1, HDAC2, HDAC3 and HDAC10 with IC50s of 95, 160, 67 and 78 nM, respectively.
View activity & pricesDC7037R306465(JNJ-16241199)
R306465, also known as JNJ-16241199, is a novel hydroxamate-based histone deacetylase (HDAC) inhibitor with broad-spectrum antitumour activity against solid and haematological malignancies in preclinical models.
View activity & pricesDC5128MC1568
MC1568 is a selective class II (IIa) histone deacetylas (HDAC II) inhibitor, used for cancer research.
View activity & pricesDC7284Scriptaid(GCK1026)
Scriptaid is a potent histone deacetylase (HDAC) inhibitor, used in cancer research.
View activity & pricesDC7716TMP269
TMP269 is a novel and selective class IIa histone deacetylase (HDAC) inhibitor with IC50s of 157 nM, 97 nM, 43 nM and 23 nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively.
View activity & pricesDC7176Quisinostat (JNJ-26481585) 2HCl
Quisinostat (JNJ-26481585) is an orally available, potent HDAC inhibitor with an IC50 of 0.11 nM for HDAC1.
View activity & pricesDC8134Trichostatin A (TSA)
Trichostatin A is a potent and specific inhibitor of HDAC class I/II, with an IC50 value of 1.8 nM for HDAC.
View activity & pricesDC7544CUDC-101
CUDC-101 is a potent inhibitor of HDAC, EGFR, and HER2 with IC50s of 4.4, 2.4, and 15.7 nM, respectively.
View activity & pricesDC9715CHR5154
GSK3117391 (CHR5154) is a HDAC inhibitor.
View activity & pricesDC8252Vorinostat (SAHA)
Vorinostat is a potent and orally available inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC7 (Class II) and HDAC11 (Class IV ), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively.
View activity & pricesDC7263RGFP 966
RGFP966 is a highly selective HDAC3 inhibitor with an IC50 of 80 nM and shows no inhibition to other HDACs at concentrations up to 15 μM.
View activity & pricesDC7196MGCD0103 (Mocetinostat)
Mocetinostat (MGCD0103) is a potent, orally active and isotype-selective HDAC (Class I/IV) inhibitor with IC50s of 0.15, 0.29, 1.66 and 0.59 μM for HDAC1, HDAC2, HDAC3 and HDAC11, respectively. Mocetinostat shows no…
View activity & pricesDC8350Droxinostat
Selective HDAC3, HDAC6 and HDAC8 inhibitor (IC50 values are 16.9, 2.47 and 1.46 μM for HDAC3, 6 and 8 respectively). Induces apoptosis. Shows antitumor effects in vivo. For the detailed information of Droxinostat, the…
View activity & pricesDC5178Tubacin (BML-GR362)
Tubacin is a potent and selective inhibitor of HDAC6, with an IC50 value of 4 nM and approximately 350-fold selectivity over HDAC1.
View activity & pricesDC8654PTACH (NCH-51)
PTACH (NCH-51) is a SAHA-based novel inhibitor of human HDAC. PTACH exerts potent growth inhibition against various human cancer cells, with EC50 values ranging from 1 to 10 μM.
View activity & pricesDC8663UF010
UF010 is a potent and selective HADC inhibitor with IC50 ~0.06 μM, 0.1 μM, 0.5 μM and 1.5 μM for HDACs 3, 2, 1 and 8, respectively. It has > 6-fold selectivity over other HDACs.IC50 value: 0.06 μM (HDAC3), 0.1 μM…
View activity & pricesDC7738CAY10683(Santacruzamate A)
Santacruzamate A is a potent and selective histone deacetylase inhibitor.
View activity & pricesDC8660BML-210(CAY10433)
BML-210 is a novel HDAC inhibitor, and its mechanism of action has not been characterized.
View activity & pricesDC7962HPOB
HPOB is a highly potent and selective inhibitor of histone deacetylase 6 (HDAC6) with IC50 of 56 nM, >30 fold less potent against other HDACs.target: HDAC6 [1]IC 50: 56nM [1]In vitro: HPOB causes growth inhibition of…
View activity & pricesDC7048Ricolinostat (ACY-1215)
Ricolinostat (ACY-1215) is a potent and selective HDAC6 inhibitor, with an IC50 of 5 nM. ACY-1215 also inhibits HDAC1, HDAC2, and HDAC3 with IC50s of 58, 48, and 51 nM, respectively.
View activity & pricesDC4241LMK-235
LMK-235 is a potent and selective HDAC4/5 inhibitor, inhibits HDAC5, HDAC4, HDAC6, HDAC1, HDAC2, HDAC11 and HDAC8, with IC50s of 4.22 nM, 11.9 nM, 55.7 nM, 320 nM, 881 nM, 852 nM and 1278 nM, respectively, and is used…
View activity & pricesDC7280Pracinostat(SB939)
Pracinostat is a potent histone deacetylase (HDAC) inhibitor, with IC50s of 40-140 nM, used for cancer research.
View activity & pricesDC7432Givinostat (ITF2357)
Givinostat hydrochloride monohydrate is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively.
View activity & pricesDC6909Entinostat (MS-275)
Entinostat is an oral and selective class I HDAC inhibitor, with IC50s of 243 nM, 453 nM, and 248 nM for HDAC1, HDAC2, and HDAC3, respectively.
View activity & pricesDC70821T-518
T-518 (T518) is a potent, highly selective, brain penetrant, oral HDAC6 inhibitor with IC50 of 36 nM.T-518 did not obviously inhibit human HDAC1, 4, or 7 at 10 uM, which belongs to Class I or Class IIa HDAC.T-518…
View activity & pricesDC2060CI994 (Tacedinaline)
CI-994 (Tacedinaline) is an inhibitor of the histone deacetylase (HDAC) with IC50s of 0.9, 0.9, 1.2 μM for recombinant HDAC 1, 2 and 3 respectively.
View activity & pricesDC8646Remodelin
Remodelin is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.Remodelin can improve nuclear architecture, chromatin organization, and fitness of both human lamin A/C-depleted cells and…
View activity & pricesDC7796Remodelin (hydrobromide)
Remodelin HBr salt is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.Remodelin can improve nuclear architecture, chromatin organization, and fitness of both human lamin A/C-depleted…
View activity & pricesDC7182Dacinostat (NVP-LAQ824, LAQ824)
Dacinostat is a potent HDAC inhibitor, with an IC50 of 32 nM; Dacinostat also inhibits HDAC1 with an IC50 of 9 nM, and used in cancer research.
View activity & pricesDC70478HDAC3 inhibitor PT3
HDAC3 inhibitor PT3 is a novel potent, selective, BBB-permeable HDAC3 inhibitor.PT3 exhibited higher selectivity for HDAC3 over HDAC1, HDAC6, and HDAC8 compared to the reference compound CI994.PT3 upregulated H3K9…
View activity & pricesDC10210TMP195
TMP195 is a selective class IIa histone deacetylase (HDAC) inhibitor with an IC50 of 300 nM.
View activity & pricesDC6304Tubastatin A
Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more).
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