DC Chemicals · Research reagents

Salt Inducible Kinase (SIK)

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YKL-06-061 chemical structureDC10778

YKL-06-061

YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively[1].

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ARN-3236 chemical structureDC10824

ARN-3236

ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2) (IC50 <1 nM), with activity in inhibiting growth and enhancing paclitaxel sensitivity in cultures and xenografts of ovarian cancer…

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