DC Chemicals · Research reagents

ADCs Linker/Click Chemistry

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Paclitaxel succinate NHS ester chemical structureDC32585

Paclitaxel succinate NHS ester

DCN10809, also known as Paclitaxel succinate NHS ester, is a paclitaxel derivative with a succinic acid linker, in which the carboxy group is activated with an NHS ester. The NHS ester group is highly reactive to amino…

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SPDP chemical structureDC22635

SPDP

SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. equal amounts of…

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Azido-PEG5-acid chemical structureDC28667

Azido-PEG5-acid

Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as the conjugate CPT-APO (CPT: Camptothecin).

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