Paclitaxel succinate NHS ester chemical structure

Chemical structureResearch use only

CAT. NO. DC32585Featured

Paclitaxel succinate NHS ester

Name: Paclitaxel succinate NHS ester
Brand: DC Chemicals
SKU: DC32585
Price: 200.0 USD

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TotalUS$200

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Product overview

Description & Application

DCN10809, also known as Paclitaxel succinate NHS ester, is a paclitaxel derivative with a succinic acid linker, in which the carboxy group is activated with an NHS ester. The NHS ester group is highly reactive to amino group or hydroxy group, and can be used to conjugate with other molecules such as peptides, proteins, antibodies or enzymes, or polymers. Paclitaxel-Succinic acid is a useful agent to make Paclitaxel-conjugate for drug delivery, nanodrug research.

Parameter	Value
Chemical Name	(1S,2R)-1-benzamido-3-(((2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-diacetoxy-12-(benzoyloxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-9-yl)oxy)-3-oxo-1-phenylpropan-2-yl (2,5-dioxopyrrolidin-1-yl) succinate
CAS No.	245110-80-9
Synonyms	Paclitaxel succinate NHS ester; DCN10809; DCN-10809; DCN 10809;
Formula	C55H58N2O19
M.Wt	1051.064
SMILES	CC1(C([C@@H](OC(C)=O)C([C@@](C)([C@]23[H])[C@@H](O)C[C@]4(OC[C@]43OC(C)=O)[H])=O)=C([C@H](C[C@]1([C@H]2OC(C5=CC=CC=C5)=O)O)OC([C@H](OC(CCC(ON6C(CCC6=O)=O)=O)=O)[C@@H](NC(C7=CC=CC=C7)=O)C8=CC=CC=C8)=O)C)C
Purity	88%
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

View online datasheet Request COA / MSDS

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Solution calculator

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