DC Chemicals · Product datasheet

Paclitaxel succinate NHS ester — Datasheet

CAT. NO. DC32585

Product page and current package options

ParameterValue
Chemical Name(1S,2R)-1-benzamido-3-(((2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-diacetoxy-12-(benzoyloxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-9-yl)oxy)-3-oxo-1-phenylpropan-2-yl (2,5-dioxopyrrolidin-1-yl) succinate
CAS No.245110-80-9
SynonymsPaclitaxel succinate NHS ester; DCN10809; DCN-10809; DCN 10809;
FormulaC55H58N2O19
M.Wt1051.064
SMILESCC1(C([C@@H](OC(C)=O)C([C@@](C)([C@]23[H])[C@@H](O)C[C@]4(OC[C@]43OC(C)=O)[H])=O)=C([C@H](C[C@]1([C@H]2OC(C5=CC=CC=C5)=O)O)OC([C@H](OC(CCC(ON6C(CCC6=O)=O)=O)=O)[C@@H](NC(C7=CC=CC=C7)=O)C8=CC=CC=C8)=O)C)C
Purity88%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

DCN10809, also known as Paclitaxel succinate NHS ester, is a paclitaxel derivative with a succinic acid linker, in which the carboxy group is activated with an NHS ester. The NHS ester group is highly reactive to amino group or hydroxy group, and can be used to conjugate with other molecules such as peptides, proteins, antibodies or enzymes, or polymers. Paclitaxel-Succinic acid is a useful agent to make Paclitaxel-conjugate for drug delivery, nanodrug research.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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