DC7341WZ 811
WZ811 is a potent CXCR4 antagonist, effectively inhibits TN14003 binding to CXCR4, with an EC50 of 0.3 nM.
View activity & pricesDC Chemicals · Research reagentsDC7341 
DC7675
DC9251
DC8741
DC8822
DC10724
DC5055
DC10773
DC7913
DC9878
DC11978
DC7429
DC10423
Chemokine Receptor (CCR and CXCR)
14 products · Page 1 of 1
All small molecule research tools
DC7341DC7675BX-471（ZK 811752）
BX471 (ZK-811752) is a potent and selective non-peptide CCR1 antagonist with a Ki of 1 nM, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
View activity & pricesDC9251RS-102895 hydrochloride
RS102895 hydrochloride is a potent CCR2 antagonist, with an IC50 of 360 nM, and shows no effect on CCR1.
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DC5056AMD3465
AMD 3465 hexahydrobromide is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4…
View activity & pricesDC8741Plerixafor octahydrochloride
Plerixafor octahydrochloride is a selective CXCR4 antagonist with an IC50 of 44 nM.
View activity & pricesDC8822MSX-122
MSX-122 is a partial antagonist of CXCR4, inhibiting CXCR4/CXCL12 actions, with an IC50 of ∼10 nM; MSX-122 has anti-inflammatory and anti-metastatic activity.
View activity & pricesDC10724AZD2098
AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor, used for asthma research.
View activity & pricesDC5055Plerixafor (AMD3100)
Plerixafor is a selective CXCR4 antagonist with an IC50 of 44 nM.
View activity & pricesDC10773AZD5069
AZD-5069 is a potent CXCR2 chemokine receptor antagonist, used for caner treatment.
View activity & pricesDC7913SB225002
SB225002 is a potent and selective CXCR2 antagonist with an IC50 of 22 nM.
View activity & pricesDC9878ATI-2341
ATI-2341, pepducin targeting the C-X-C chemokine receptor type 4 (CXCR4), is an allosteric agonist activating the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium…
View activity & pricesDC11978SB 265610
SB-265610 is a selective, competitive, nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis with…
View activity & pricesDC7429INCB 8761
PF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50 of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2.
View activity & pricesDC10423Motixafortide(BKT140)
BKT140 4-fluorobenzoyl is a novel CXCR4 antagonist with an IC50 vakue of ～1 nM. Sequence: 4F-Benzoyl-Arg-Arg-{2-Naph-Ala}-Cys-Tyr-{Cit}-Lys-Lys-Pro-Tyr-Arg-{Cit}-Cys-Arg-NH2(Disulfide bridge: Cys4-Cys13).
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