DC10373WEHI-345
WEHI-345 is a potent and selective inhibitor of RIPK2, with IC50 of 0.13 μM.
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DC10373WEHI-345 is a potent and selective inhibitor of RIPK2, with IC50 of 0.13 μM.
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DC10787GSK2982772 is a potent and ATP competitive RIP1 inhibitor with an IC50 of 16 nM.
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DC9721GSK2983559 active metabolite is a receptor interacting protein-2 (RIP2) kinase inhibitor extracted from patent WO/2014043446 A1, compound example 1.
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DC9733GSK583 is a highly potent and selective inhibitor of RIP2 Kinase, with IC50 of 5 nM.
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DC10471GSK'872 is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC50 of 1.8 nM, and inhibits kinase activity with an IC50 of 1.3 nM.
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DC73130AC-003 is a novel, orally administered small-molecule inhibitor targeting receptor-interacting protein kinase 1 (RIPK1), demonstrating therapeutic potential for the treatment of idiopathic pulmonary fibrosis (IPF).
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DC12045HS-1371 is a potent and ATP-competitive RIP3 inhibitor with an IC50 of 20.8 nM[1].
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