DC Chemicals · Research reagents

Bacterial Infection

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All small molecule research tools

Fidaxomicin (Dificid) chemical structureDC1057

Fidaxomicin (Dificid)

Fidaxomicin(OPT-80; PAR-101) is a new class of narrow spectrum macrocyclic antibiotic drug; selective eradication of pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria that…

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Q203 chemical structureDC10109

Q203

Q203 (IAP6) is a midazopyridine amide compound. Q203 is active against Mycobacterium tuberculosis H37Rv with an MIC50 of 2.7 nM in culture broth medium.

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PBTZ169 chemical structureDC9723

PBTZ169

Macozinone is a new drug candicate that inhibits decaprenylphosphoryl-β-d-ribose 2′-oxidase (DprE1), more efficiently than BTZ043target: DprE1In vitro: PBTZ169, inhibit decaprenylphosphoryl-β-d-ribose 2′-oxidase…

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AN3365(Epetraborole) chemical structureDC9827

AN3365(Epetraborole)

Epetraborole hydrochloride is a novel leucyl-tRNA synthetase (LeuRS) inhibitor, which inhibits protein synthesis by binding "to the terminal adenosine ribose (A76) of leucyl-tRNA synthetase". It is intended for the…

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Relebactam chemical structureDC10441

Relebactam

Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases [ESBLs] and KPC) and class C (AmpC) enzymes.Target:…

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Solithromycin chemical structureDC8032

Solithromycin

Solithromycin is a novel fluoroketolide with improved antimicrobial effectiveness.Solithromycin binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis. The mean 50% inhibitory concentrations…

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SPR741 (NAB741) chemical structureDC27000

SPR741 (NAB741)

SPR741 (NAB741) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative…

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AFN-1252(Debio 1452) chemical structureDC10513

AFN-1252(Debio 1452)

AFN-1252(Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibited all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of ≤0.12 μg/ml. IC50…

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PD 404182 chemical structureDC12012

PD 404182

PD 404182 is a potent and competitive inhibitor of human dimethylarginine dimethylaminohydrolase 1 (DDAH1), with an IC50 of 9 μM. PD 404182 exhibits antiangiogenic and antiviral activity in vitro[1][2].

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Moxifloxacin hydrochloride chemical structureDC4226

Moxifloxacin hydrochloride

For the detailed information about the solubility of Moxifloxacin hydrochloride in water, the solubility of Moxifloxacin hydrochloride in DMSO, the solubility of Moxifloxacin hydrochloride in PBS buffer, the animal…

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Sutezolid (PNU-100480) chemical structureDC10733

Sutezolid (PNU-100480)

Sutezolid (PNU-100480) is an oxazolidinone antimicrobial being developed for the treatment of tuberculosis.Target: AntibacterialSutezolid is a much-awaited drug candidate for treatment of Mycobacterium tuberculosis.…

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Murepavadin (POL7080) chemical structureDC11273

Murepavadin (POL7080)

Murepavadin (POL7080) is a highly potent, specific, macrocycle Pseudomonas antibiotic for the treatment of bacterial infections caused by Pseudomonas aeruginosa. Bacterial Infection Phase 3 Clinical

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Rifabutin (Mycobutin) chemical structureDCAPI1325

Rifabutin (Mycobutin)

For the detailed information of Rifabutin (Mycobutin), the solubility of Rifabutin (Mycobutin) in water, the solubility of Rifabutin (Mycobutin) in DMSO, the solubility of Rifabutin (Mycobutin) in PBS buffer, the…

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