5-HT Receptor

16 products · Page 1 of 1

All small molecule research tools

DC11399

AVN-492

AVN-492 is a very specific and highly-selective antagonist with picomolar affinity to 5-HT6R (Ki=91 pM).

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DC9313

Sarpogrelate (hydrochloride)

Sarpogrelate(MCI-9042) hydrochloride, a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD.Sarpogrelate is a drug which acts as an antagonist at the 5HT2A and 5-HT2B…

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DC7884

LY310762

LY310762 is a 5-HT1D receptor antagonist with Ki of 249 nM, having a weaker affinity for 5-HT1B receptor.IC50 value: 249 nM (Ki) [1]Target: 5-HT1D in vitro: LY310762 has a higher affinity for the guinea pig 5-HT1D…

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DC9260

Eptapirone

F 11440 is a potent, selective, high efficacy 5-HT1A receptor agonist with marked anxiolytic and antidepressant potential.Target: 5-HT1AThe affinity of F 11440 for 5-HT1Abinding sites (pKi, 8.33) was higher than that…

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DC8334

RS-127445

RS-127445 is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist with a pKi of 9.5. RS-127445 shows 1000 fold selectivity for this receptor as compared to numerous other receptor and ion channel…

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DC8795

Pimavanserin(ACP-103)

Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC50 and pKd of 8.73 and 9.3, respectively.

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DC9915

PF04995274,PF 04995274

PF-04995274 is a potent, high-affinity, orally active and partial serotonin 4 receptor (5-HT4R) agonist. PF-04995274 has an EC50 range of 0.26-0.47 nM for human 5-HT4A/4B/4D/4E (Ki range of 0.15-0.46 nM), and has an…

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DC8354

Intepirdine (SB-742457, RVT-101）

SB742457 is a highly selective 5-HT6 receptor antagonist with pKi of 9.63; exhibits >100-fold selectivity over other receptors.SB-742457, a 5-HT6 receptor antagonist, which extends into Alzheimer disease (AD) sufferers…

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DC72326

Tabernanthalog

Tabernanthalog is a water-soluble, non-hallucinogenic and non-toxic analogue of ibogaine. Tabernanthalog is a 5-HT2A agonist. Tabernanthalog is found to promote structural neural plasticity, reduce alcohol- and…

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DC9059

Olanzapine

Olanzapine(LY170053) is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist.IC50 Value:Target: 5-HT ReceptorOlanzapine is a thienobenzodiazepine that blocks especially the serontonin…

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DC8755

WAY 100635 Hydrochloride

WAY 100635 Hydrochloride is available from DC Chemicals for laboratory research. Contact us for application-specific product information.

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DC7268

Risperidone(R 64 766)

Risperidone(Risperdal) is an atypical antipsychotic used to treat schizophrenia (including adolescent schizophrenia), schizoaffective disorder, the mixed and manic states associated with bipolar disorder, and…

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DC9147

Aripiprazole

Aripiprazole(Abilify) is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM.Aripiprazole is an atypical antipsychotic medication used for the treatment of schizophrenia. It has also recently received FDA…

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DC9150

Tianeptine sodium salt

Tianeptine sodium salt is a selective facilitator of 5-HT uptake in vitro and in vivo.Tianeptine has no affinity for a wide range of receptors, including 5-HT and dopamine (IC50 > 10 μM) and has no effect on…

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DC4102

SB-269970

SB269970 is a 5-HT7 receptor antagonist with pKi of 8.3, exhibits >50-fold selectivity against other receptors.

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DC7494

SB 242084 dihydrochloride

IC50 value: 9.0(pKi) [1]Target: 5-HT2C antagonist

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