DC7194MDL 29951
MDL-29951 is a novel glycine antagonist of NMDA receptor activation, with Ki of 0.14 μM for [3H]glycine binding in vitro and in vivo.
View activity & pricesDC Chemicals · Research reagentsDC7194 
DC8156
DC5075
DC7226
DC7989
DC7961
DC7960
DC10670
DC10672
DC10671
DC10673
DC10382
DC7863
DC11197
DC9341
iGluR
15 products · Page 1 of 1
All small molecule research tools
DC7194DC8156CIQ
CIQ is a subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit. IC50 value: 2.7 μM (EC50, for NR2C) and 2.8 μM (EC50, NR2D)Target: NMDA receptorCIQ increases channel opening frequency of…
View activity & pricesDC5075BDP-12(Ampalex)
Ampalex (Ampakine CX516; CX516; BDP 12) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI).
View activity & pricesDC7226Perampanel(E2007）
Perampanel(E2007; ER 155055-90) is a selective noncompetitive AMPA-type glutamate receptor antagonist which has demonstrated anticonvulsant activity in experimental seizure models and antiepileptic activity in clinical…
View activity & pricesDC7989PEPA
PEPA is an allosteric modulator of AMPA receptors; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity.
View activity & pricesDC7961(-)MK-801 maleate
(-)-MK 801 Maleate is the enantiomer of (+)-MK-801. (+)-MK 801 Maleate is a potent, selective and non-competitive NMDA receptor antagonist.
View activity & pricesDC7960(+)MK-801 maleate
(+)-MK 801 Maleate is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.
View activity & pricesDC10670CNQX
CNQX (FG9065) is a potent AMPA/kainate receptor antagonist.
View activity & pricesDC10672DNQX
DNQX is a AMPA receptor antagonists.target: AMPA receptorIn vitro: DNQX, added 2 h after cell plating, induces a dose-dependent neurotoxicity.
View activity & pricesDC10671CNQX disodium salt
CNQX is a potent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex.
View activity & pricesDC10673DNQX disodium salt
DNQX (FG 9041) disodium salt, a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively)[1].
View activity & pricesDC10382Farampator
Farampator (CX-691;Org24448) is an AMPA receptor positive modulator.
View activity & pricesDC7863Talampanel (GYKI 53773)
Talampanel is a potent and selective AMPA-receptor antagonist, is a potential new antiepileptic drug (AED).
View activity & pricesDC11197UoS12258
UoS12258 (UoS-12258) is a selective, positive allosteric modulator of the AMPA receptor with pEC50 of 5.6; displays excellent wide selectivity against a wide range of other ion channels (including hERG, NMDA, and…
View activity & pricesDC9341Naspm
Naspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
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