Small Molecule Research Tools

2816 products · Page 59 of 59

DC49170

Erastin2

Erastin2 is a ferroptosis inducer and a potent, selective inhibitor of the system xc(-) cystine/glutamate transporter.

View activity & prices

DC8725

NSC 23766 trihydrochloride

NSC 23766 trihydrochloride is an inhibitor of Rac1 activation.

View activity & prices

DC10540

NVP-BQR695 (BQR-695)

BQR-695 is a PI4KIIIβ inhibitor with IC50s of 80 and 3.5 nM for human PI4KIIIβ and Plasmodium variant of PI4KIIIβ, respectively.

View activity & prices

DC39818

CL2-SN-38 (dichloroacetic acid salt)

CL2-SN-38 is a cleavable linker-based antibody-drug conjugate (ADC) containing the topoisomerase I inhibitor SN-38 (Item No. 15632) and a maleimidocaproyl linker.1 CL2-SN-38 has been linked to tumor-selective human…

View activity & prices

DC12667

SCR-1481B1 (BMS-817378, bis-Tris salt)

SCR-1481B1 (c-Met inhibitor 2) is a potent compound that has activity against cancers dependent upon Met activation and also has activity against cancers as a VEGFR inhibitor.

View activity & prices

DC23688

LY-3000328

LY-3000328 is a potent, highly selective cathepsin S inhibitor with IC50 of 7.7 nM; dispalys >500-fold selectivity over cathepsin L, cathepsint K, cathepsin B, and cathepsin V; shows efficacy in a CaCl2-induced AAA…

View activity & prices

DC23157

Naspm trihydrochloride

Naspm is a selective antagonist of Ca2+-permeable AMPA receptors, blocks GluR2-lacking AMPARs, suppresses current responses induced by kainate in type II neurons with IC50 of 0.33 uM; greatly reduces the late rise in…

View activity & prices

DC72545

MK-571 sodium salt

MK-571 sodium salt (L-660711) is a selective, orally active antagonist of leukotriene D4 receptor. It is also an inhibitor of multidrug resistance-associated protein MRP4 (ABCC4) and ABCC1 (MRP1).

View activity & prices

DC9242

Imatinib (free base)

Imatinib is a tyrosine kinases inhibitor that inhibits c-Kit, Bcr-Abl, and PDGFR (IC50=100 nM) tyrosine kinases.

View activity & prices

DCAPI1468

Rosuvastatin Calcium

Rosuvastatin Calcium is a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM.

View activity & prices

DC26139

2-(5-Chloro-1H-indol-2-yl)acetic acid

2-(5-Chloro-1H-indol-2-yl)acetic acid|CAS 720000-48-6

View activity & prices

DC3150

Atazanavir

Atazanavir(BMS-232632) is an highly potent HIV-1 protease inhibitor.Atazanavir sulfate is a sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor. It has a pharmacokinetic profile that…

View activity & prices

DC9553

Carbetocin

Carbetocin (Lonactene; Duratocin) is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth; an agonist at peripheral oxytocin receptors.

View activity & prices

DC10097

ROC-325

ROC-325 is a novel inhibitor of autophagy.

View activity & prices

DC9180

Tamoxifen Citrate

Tamoxifen Citrate is a selective estrogen receptor modulator (SERM).

View activity & prices

DC8779

Glycopyrrolate

Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.

View activity & prices

DC12024

ARV-825

ARV-825 is a hetero-bifunctional proteolysis-targeting chimera (PROTAC) that recruits BRD4 to the E3 ubiquitin ligase cereblon. ARV-825 actively recruits BRD4 to cereblon, resulting in the rapid and efficient…

View activity & prices

DC23902

Ifenprodil tartrate (2:1)

Ifenprodil tartrate is a novel N-methyl-D-aspartate (NMDA) receptor antagonist that selectively inhibits receptors containing the NR2B subunit.

View activity & prices

DC10055

Akt-I-1,2 HCl

The compound (Akt-I-1,2) inhibited both Akt1 and Akt2 with IC50 values of 2.7 and 21 μM respectively. It does not inhibit AKT3. The compound is a reversible inhibitor, and exhibits a linear mixed-type inhibition…

View activity & prices

DC9098

Paroxetine hydrochloride hemihydrate

Paroxetine hydrochloride hemihydrate is a potent selective serotonin-reuptake inhibitor, commonly prescribed as an antidepressant and has GRK2 inhibitory ability with IC50 of 14 μM.

View activity & prices

DC6314

Icatibant acetate

Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively[1][2][3].

View activity & prices

DC8947

Meldonium dihydrate (Mildronate)

Meldonium dihydrate (Mildronate) is available from DC Chemicals for laboratory research. Contact us for application-specific information.

View activity & prices

DC21504

PF-719

PF-719 (PF719) is a potent, selective Pyk2 inhibitor with IC50 of 17 nM, displays 25-fold selectvity over FAK (IC50=469 nM); does not have significant inhibitory effects on recombinant MLCK2, p38, Akt1, or ROCK1, and…

View activity & prices

DC9341

Naspm

Naspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.

View activity & prices

DC23142

GW274150

GW274150 is a novel arginine-competitive, NADPH-dependent iNOS inhibitor that has been identified from a series of acetamide amino acids that have a high selectivity for iNOS vs both eNOS (> 260-fold) and nNOS (>…

View activity & prices

DC73619

Org 34167 hydrochloride

Org 34167 HCl salt is a broad-spectrum inhibitor of HCN channels with IC50 of 23.4, 8.2 and 9.2 uM for HCN1, HCN2 and HCN4 channels, respectively, slowing activation and causing a hyperpolarising shift in…

View activity & prices

DCAPI1411

Bisoprolol fumarate (2:1)

Bisoprolol, on beta 1-adrenoceptor pBisoprolol is a selective type β1 adrenergic receptor blocker.Approved: July 31, 1992Bisoprolol, on beta 1-adrenoceptor peptide induced autoimmune myocardial damage. In the animal…

View activity & prices

DC10120

MC-Val-Cit-PAB

MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.

View activity & prices

DC31666

Doxycycline Hyclate

Doxycycline Hyclate is the hyclate salt form of a synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity. It is an antimicrobial tetracycline that acts as an inhibitor of a wide range of…

View activity & prices

DCAPI1442

Atorvastatin calcium

For the detailed information of Atorvastatin Calcium, the solubility of Atorvastatin Calcium in water, the solubility of Atorvastatin Calcium in DMSO, the solubility of Atorvastatin Calcium in PBS buffer, the animal…

View activity & prices

DC11426

DM1-PEG4-DBCO

DM1-(PEG)4-DBCO (DBCO-PEG4-DM1) is made by DM1 conjugated to DBCO-(PEG)4 linker.DM1 (mertansine), a thiol-containing maytansinoid, is a potent microtubule-disrupting agent.

View activity & prices

DC3148

Duloxetine

Duloxetine is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). Duloxetine inhibits the reuptake of serotonin and…

View activity & prices