Dyslipidemia

9 products · Page 1 of 1

All small molecule research tools

DC10700

Seladelpar

Seladelpar is an orally active, potent (50% effect concentration EC50 2 nM), and specific PPAR-δ agonist.

View activity & prices

DC4233

GW501516

GW 501516 is a PPARδ agonist with an EC50 of 1.1 nM.

View activity & prices

DC11360

Pemafibrate

Pemafibrate is a potent PPARα agonist, with EC50s of 1 nM, 1.10 μM and 1.58 μM for h-PPARα, h-PPARγ and h-PPARδ, respectively, and possesses lipid-lowering effect.

View activity & prices

DC1094

Avasimibe

Avasimibe is an oral inhibitor of acyl-Coenzyme A:cholesterol acyltransferase (ACAT) with IC50s of 24 and 9.2 µM for ACAT1 and ACAT2, respectively.

View activity & prices

DC7125

Evacetrapib (LY2484595)

Evacetrapib is a potent and selective of CETP inhibitor, which inhibits human recombinant CETP protein (IC50 5.5 nM) and CETP activity in human plasma (IC50 36 nM) in vitro.

View activity & prices

DC9252

BMS-687453

BMS-687453 is a potent and selective PPARα agonist, with an EC50 and IC50 of 10 nM and 260 nM for human PPARα and 4100 nM and >15000 nM for PPARγ in PPAR-GAL4 transactivation assays.

View activity & prices

DCAPI1349

Simvastatin (Zocor)

Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM.

View activity & prices

DCAPI1468

Rosuvastatin Calcium

Rosuvastatin Calcium is a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM.

View activity & prices

DCAPI1442

Atorvastatin calcium

For the detailed information of Atorvastatin Calcium, the solubility of Atorvastatin Calcium in water, the solubility of Atorvastatin Calcium in DMSO, the solubility of Atorvastatin Calcium in PBS buffer, the animal…

View activity & prices