DC1001FK-506 (Tacrolimus)
Tacrolimus is a macrocyclic lactone with potent immunosuppressive properties. Tacrolimus binds to FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase.
View activity & pricesDC Chemicals · Research reagentsDC1001 
DC1501
DC7482
DCAPI1488
DC3117
DC8377
DC7171
DC3118
DC7210
DC1006
DC10125
DC1048
DC5084
mTOR
13 products · Page 1 of 1
All small molecule research tools
DC1001DC1501Everolimus
Everolimus (RAD001) is a potent mTOR inhibitor that binds to FKBP-12 to generate an immunosuppressive complex.
View activity & pricesDC7482Torkinib (PP242)
Torkinib (PP 242) is a selective and ATP-competitive mTOR inhibitor with an IC50 of 8 nM. PP242 inhibits both mTORC1 and mTORC2 with IC50s of 30 nM and 58 nM, respectively.
View activity & pricesDCAPI1488Temsirolimus
Temsirolimus is an inhibitor of mTOR with an IC50 of 1.76 μM.
View activity & pricesDC3117Torin2
Torin 2 is an mTOR inhibitor with EC50 of 0.25 nM for inhibiting cellular mTOR activity, and exhibits 800-fold selectivity over PI3K (EC50: 200 nM). Torin 2 also inhibits DNA-PK with an IC50 of 0.5 nM in the cell free…
View activity & pricesDC8377CC-115
CC-115 is a potent and dual DNA-PK and mTOR kinase inhibitor with IC50s of 13 nM and 21 nM, respectively. CC-115 blocks both mTORC1 and mTORC2 signaling.
View activity & pricesDC7171INK-128(Sapanisertib)
Sapanisertib (INK-128) is a ATP-dependent mTOR1/2 inhibitor with an IC50 of 1 nM for mTOR kinase.
View activity & pricesDC3118Torin1
Torin 1 is a potent inhibitor of mTOR with an IC50 of 3 nM. Torin 1 inhibits both mTORC1/2 complexes with IC50 values between 2 and 10 nM.
View activity & pricesDC7210LY-303511(Nv-128)
LY303511 is a structural analogue of LY294002. LY303511 does not inhibit PI3K. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells. LY303511 reversibly blocks K+ currents (IC50=64.6±9.1 μM) in MIN6…
View activity & pricesDC1006OSI-027
OSI-027 is an ATP-competitive mTOR kinase activity inhibitor with an IC50 of 4 nM. OSI-027 targets both mTORC1 and mTORC2 with IC50s of 22 nM and 65 nM, respectively.
View activity & pricesDC10125CZ415
CZ415 is a potent and highly selective mTOR inhibitor with a pIC50 of 8.07. CZ415 inhibits mTORC1 and mTORC2 protein complex.
View activity & pricesDC1048Rapamycin (Sirolimus)
Rapamycin (Sirolimus) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM.
View activity & pricesDC5084AZD-8055
AZD-8055 is a novel ATP-competitive inhibitor of mTOR kinase with an IC50 of 0.8 nM. AZD-8055 inhibits both mTORC1 and mTORC2.
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