DC7994Afuresertib HCl
Afuresertib hydrochloride is a potent and ATP-competitive specific Akt inhibitor.
View activity & pricesDC Chemicals · Research reagentsDC7994 
DC8458
DC7465
DC2070
DC5163
DC9273
DC9335
DC8333
DC9972
DC10408
DC7481
DC10055
Akt
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All small molecule research tools
DC7994DC8458Akt Inhibitor VIII
AKT inhibitor VIII is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC50s of 58 nM, 210 nM, and 2119 nM,…
View activity & pricesDC7465MK-2206 2HCl
MK 2206 is an orally active allosteric Akt inhibitor with IC50s of 5, 12 and 65 nM for Akt1, Akt2 and Akt3, respectively.
View activity & pricesDC2070GSK690693
GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2/13/9 nM in cell-free assays, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes.
View activity & pricesDC5163A-674563
A-674563 is a potent selective Akt1 (Protein Kinase B) inhibitor (IC50 = 14 nM). A-674563 also shows inhibitory activity against PKA and Cdk2 (IC50’s: PKA = 16 nM; Cdk2 = 46 nM). A-674563 has been shown to have a…
View activity & pricesDC9273SC-66
SC66 is a novel Akt inhibitor, reduces cell viability in a dose- and time-dependent manner, inhibits colony formation and induces apoptosis in hepatocellular carcinoma (HCC) cells.
View activity & pricesDC9335AT7867
AT7867 is a potent ATP-competitive inhibitor of Akt1/Akt2/Akt3 and p70S6K/PKA with IC50s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively.
View activity & pricesDC8333SC-79
SC79 is a selective and cell-permeable Akt activator which activates Akt phosphorylation and inhibits Akt membrane translocation.
View activity & pricesDC9972ARQ-092(Miransertib)
ARQ-092 is an orally bioavailable, selective, and potent allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively.
View activity & pricesDC10408BAY1125976
BAY1125976 is a selective allosteric Akt1/Akt2 inhibitor; inhibits Akt1 and Akt2 activity with IC50 values of 5.2 nM and 18 nM at 10 μM ATP, respectively.
View activity & pricesDC7481PHT427
PHT-247 is an inhibitor of the pleckstrin homology (PH) domain of Akt, and it is also an inhibitor of PDPK1 with Kis of 2.7 µM and 5.2 µM and for Akt and PDPK1, respectively.
View activity & pricesDC10055Akt-I-1,2 HCl
The compound (Akt-I-1,2) inhibited both Akt1 and Akt2 with IC50 values of 2.7 and 21 μM respectively. It does not inhibit AKT3. The compound is a reversible inhibitor, and exhibits a linear mixed-type inhibition…
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