DC Chemicals · Research reagents

Integrin

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GLPG0187 chemical structureDC10034

GLPG0187

GLPG0187 is a broad spectrum integrin receptor antagonist with antitumor activity; inhibits αvβ1-integrin with an IC50 of 1.3 nM.

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CWHM-12 chemical structureDC9278

CWHM-12

CWHM-12 is a potent inhibitor of αV integrins with IC50s of 0.2, 0.8, 1.5, and 1.8 nM for αvβ8, αvβ3, αvβ6, and αvβ1.

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Cyclo(-RGDfK) chemical structureDC8055

Cyclo(-RGDfK)

Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM. Sequence: Cyclo(Arg-Gly-Asp-Phe-Lys).

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