Chemical structureResearch use only

CAT. NO. DC8399Featured

Cyclo(RGDyK)

Name: Cyclo(RGDyK)
Brand: DC Chemicals
SKU: DC8399
Price: 550.0 USD

Pack Sizes & Prices

TotalUS$550

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Product overview

Description & Application

Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.

Parameter	Value
Chemical Name	Cyclo(RGDyK) trifluoroacetate
CAS No.	250612-42-1
Synonyms	Cyclic Arg-Gly-Asp-D-Tyr-Lys;Cyclo(RGDyK);AK685805;Cyclo(RGDyK) trifluoroacetate
Formula	C31H43F6N9O12
M.Wt	847.716648340225
SMILES	FC(C(=O)O)(F)F.FC(C(=O)O)(F)F.O=C1C(CCCCN)NC(C(CC2C=CC(=CC=2)O)NC(C(CC(=O)O)NC(CNC(C(CCC/N=C(\N)/N)N1)=O)=O)=O)=O
Purity	>98%
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.

In Vitro

Cyclo(RGDyK) (c(RGDyK(SAA)) shows high affinity and selectivity for αVβ3 over αVβ5 (IC50=4000 nM) and αIIbβ3 (IC50=3000 nM)[1].

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

View online datasheet Request COA / MSDS

Refer to the certificate supplied with your lot for batch-specific release results.

Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Solution calculator

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