Org 34167 hydrochloride chemical structure
Chemical structureResearch use onlyView full-size structure
CAT. NO. DC73619Featured

Org 34167 hydrochloride

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Product overview

Description & Application

Org 34167 HCl salt is a broad-spectrum inhibitor of HCN channels with IC50 of 23.4, 8.2 and 9.2 uM for HCN1, HCN2 and HCN4 channels, respectively, slowing activation and causing a hyperpolarising shift in voltage-dependence of activation.

ParameterValue
Chemical NameOrg 34167 hydrochloride
CAS No.198966-49-3
SynonymsOrg 34167
FormulaC17H17ClN2O
M.Wt300.79
SMILESC=CC[C@H](N)c1ccccc1-c1noc2ccccc12.Cl
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Chemical identity references

Biological Activity

Org 34167 HCl salt is a broad-spectrum inhibitor of HCN channels with IC50 of 23.4, 8.2 and 9.2 uM for HCN1, HCN2 and HCN4 channels, respectively, slowing activation and causing a hyperpolarising shift in voltage-dependence of activation.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

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References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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