DC Chemicals · Research reagents

HCN Channel

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NUCC-0200590 chemical structureDC73618

NUCC-0200590

NUCC-0200590 is a small-molecule inhibitor of the TRIP8b-HCN interaction with IC50 of 7.0 uM in AlphaScreen assays, effectively disrupts the TRIP8b-HCN interaction in vitro and in vivo.

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Org 34167 hydrochloride chemical structureDC73619

Org 34167 hydrochloride

Org 34167 HCl salt is a broad-spectrum inhibitor of HCN channels with IC50 of 23.4, 8.2 and 9.2 uM for HCN1, HCN2 and HCN4 channels, respectively, slowing activation and causing a hyperpolarising shift in…

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