DC Chemicals · Research reagents

RET Tyrosine Kinase (c-RET)

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Selpercatinib(LOXO-292) chemical structureDC11450

Selpercatinib(LOXO-292)

Selpercatinib is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 163, has an IC50 of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M) , and RET (G810R), respectively[1].…

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Enbezotinib chemical structureDC48424

Enbezotinib

Enbezotinib, an inhibitor of RET, can inhibit the RET autophosphorylation. Enbezotinib can be used for the research of cancer[1].

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