DC3132VE-821
VE-821 is a potent ATP-competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM.
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DC10080
DC4112
DC7448
DC8468
DC1067
DC39113
DC10526
ATM/ATR
8 products · Page 1 of 1
All small molecule research tools
DC3132DC10080GJ103 (sodium salt)
GJ103 sodium salt is an active analog of the read-through compound GJ072.
View activity & pricesDC4112CP466722
CP-466722 is a rapidly reversible inhibitor of ATM, with an IC50 of 4.1 μM, and has no effects on PI3K or closely related PI3K-like protein kinase (PIKK) family members.
View activity & pricesDC7448KU-60019
KU-60019 is an improved ATM kinase-specific inhibitor with IC50 of 6.3 nM.
View activity & pricesDC8468Ceralasertib (AZD6738)
AZD6738 is a potent inhibitor of ATR kinase with an IC50 of 1 nM.
View activity & pricesDC1067KU-55933
KU-55933 is a potent ATM inhibitor with an IC50 and Ki of 12.9 and 2.2 nM, respectively, and is highly selective for ATM as compared to DNA-PK, PI3K/PI4K, ATR and mTOR.
View activity & pricesDC39113Gartisertib
Gartisertib (VX-803) is an ATP-competitive, orally active, and selective ATR inhibitor, with a Ki of <150 pM. Gartisertib potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (Chk1) phosphorylation with an…
View activity & pricesDC10526Elimusertib hydrochloride (BAY 1895344 hydrochloride)
BAY-1895344 is a potent, orally available and selective ATR inhibitor, with IC50 of 7 nM. Anti-tumor activity[1].
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