Sirtuin

9 products · Page 1 of 1

All small molecule research tools

DC7540

SIRT2 Inhibitor II, AK-7

AK-7 is a selective cell- and brain-permeable SIRT2 inhibitor, with an IC50 of 15.5 μM.

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DC8900

SRT1720

SRT 1720 is a selective activator of human SIRT1 with an EC1.5 of 0.16 μM, and shows less potent activities agaiinst SIRT2 and SIRT3 with EC1.5s of 37 μM and > 300 μM, respectively.

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DC7539

SIRT2 Inhibitor II, AK-1

AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor.

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DC10616

3-TYP

3-TYP is a selective SIRT3 inhibitor, with an IC50 of 16 nM, more potent over SIRT1 (IC50=88 nM), SIRT2 (IC50=92 nM).

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DC8437

AGK2

AGK2 is a selective SIRT2 inhibitor with IC50 of 3.5 μM. AGK2 can also inhibit SIRT1 and SIRT3 with IC50 of 30 and 91 μM, respectively.

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DC7127

EX-527(Selisistat)

Selisistat (EX-527) is a potent and selective SIRT1 inhibitor with IC50 of 98 nM.

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DC10658

OSS-128167(SIRT6-IN-1)

OSS_128167 is a selective SIRT6 inhibitor with IC50s of 89, 1578 and 751 μM for SIRT6, SIRT1 and SIRT2, respectively.

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DC8412

SRT2104

SRT 2104 is a brain-permeable activator of SIRT1, used for the research of type 2 diabetes mellitus and Huntington's disease.

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DC7300

SRT1720 HCl

SRT 1720 Hydrochloride is a selective activator of SIRT1 with an EC1.5 of 0.16 μM, and shows less potent activities on SIRT2 and SIRT3 with EC1.5s of 37 μM and 300 μM, respectively.

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