DC7241PND-1186
PND-1186 is a potent and reversible inhibitor of FAK with an IC50 of 1.5 nM in cell assay.
View activity & pricesDC Chemicals · Research reagentsDC7241 
DC7941
DC7695
DC7885
DC4106
DC8376
DC8331
DC3169
DC9446
DC3168
DC8526
Focal Adhesion Kinase (FAK)
11 products · Page 1 of 1
All small molecule research tools
DC7241DC7941PF-431396
PF-431396 is dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor (IC50 values are 2 and 11 nM respectively), PF-431396 has a Kd value of 445 nM for BRD4.
View activity & pricesDC7695Defactinib (VS-6063, PF-04554878)
Defactinib is a novel FAK inhibitor with potential antiangiogenic and antineoplastic activities.
View activity & pricesDC7885NVP-TAE226
NVP-TAE 226 is a dual tyrosine kinase inhibitor of FAK (IC50=5.5 nM) and IGF-IR (mean IC50=0.14 μM).
View activity & pricesDC4106PF573228
PF-573228 is a potent and selective FAK inhibitor with IC50 of 4 nM for purified recombinant catalytic fragment of FAK.
View activity & pricesDC8376TAS-301
TAS-301 is an inhibitor of smooth muscle cell migration and proliferation, and inhibits PKC activation induced by PDGF.
View activity & pricesDC8331GSK2256098
GSK2256098 is a selective FAK kinase inhibitor, which inhibits growth and survival of pancreatic ductal adenocarcinoma cells.
View activity & pricesDC3169PF-562271
PF-562271 is a potent ATP-competitive, reversible inhibitor of FAK and Pyk2 kinase, with an IC50 of 1.5 nM and 13 nM, respectively.
View activity & pricesDC9446Y15
Y15 is a direct and specific inhibitor of FAK auto-phosphorylation.
View activity & pricesDC3168PF-562271 besylate
PF-562271 (besylate) is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 kinase with IC50 of 1.5 nM and 13 nM, and has > 100-fold selectivity against other protein kinases, except for some CDKs.
View activity & pricesDC8526PF4618433
PF-4618433 is a potent and selective PYK2 inhibitor, with an IC50 of 637 nM. PF-4618433 may be suitable for the research of osteoporosis, craniofacial and appendicular skeletal defects and for targeted bone…
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