DC4179Niraparib(MK4827) free base
Niraparib (MK-4827) is a highly potent PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively.
View activity & pricesDC Chemicals · Research reagentsDC4179 
DC3170
DC7522
DC7140
DC9576
DC8630
DC7191
DC10070
DC8655
DC8464
DC3156
DC10657
DC4110
DC11641
Ovarian Cancer
14 products · Page 1 of 1
All small molecule research tools
DC4179DC3170Cediranib
Cediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR tyrosine kinase inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.
View activity & pricesDC7522Triapine
Triapine is a novel inhibitor of the M2 subunit of ribonucleotide reductase (RR), and is a potent radiosensitizer.
View activity & pricesDC7140GSK1070916
GSK-1070916 is a potent and selective ATP-competitive inhibitor of aurora B and aurora C with Kis of 0.38 and 1.5 nM, respectively, and is >250- fold selective over Aurora A.
View activity & pricesDC9576Niraparib tosylate
Niraparib tosylate (MK-4827 tosylate) is an excellent PARP1 and PARP2 inhibitor with an IC50 of 3.8 and 2.1 nM, respectively.
View activity & pricesDC8630Ralimetinib 2MsOH(LY2228820)
Ralimetinib dimesylate (LY2228820) is a selective, ATP-competitive inhibitor of p38 MAPK α/β with IC50s of 5.3 and 3.2 nM, respectively.
View activity & pricesDC7191LY-2940680(Taladegib)
Taladegib (LY2940680) is an antagonist of the smoothened receptor.
View activity & pricesDC10070PRIMA-1MET(APR-246)
PRIMA-1MET restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells. PRIMA-1MET also targets the selenoprotein thioredoxin reductase 1 (TrxR1), a key regulator of cellular redox…
View activity & pricesDC8655Vatalanib free base
Vatalanib free base (PTK787 free base) is an inhibitor of VEGFR2/KDR with IC50 of 37 nM, less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4.in vitro: Vatalanib also inhibits Flk, c-Kit and PDGFRβ with IC50…
View activity & pricesDC8464Rucaparib(AG-014447)
Rucaparib is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, and also shows binding affinity to eight other PARP domains.
View activity & pricesDC3156Elesclomol (STA-4783)
Elesclomol is an oxidative stress inducer that induces cancer cell apoptosis.
View activity & pricesDC10657COTI-2
COTI-2 is a small molecule candidate anti-cancer drug which can convert mutant p53 to wild-type conformation.
View activity & pricesDC4110AZD-2281 (Olaparib)
Olaparib (AZD2281;KU0059436) is a potent and oral PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively.
View activity & pricesDC11641Cridanimod
Cridanimod is a small-molecule immunomodulator and interferon inducer[1]. Cridanimod is a potent progesterone receptor (PR) activator mediated through induction of IFNα and IFNβ expression[2].
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