DC Chemicals · Research reagents

Exportin-1 (CRM1,XPO1)

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KPT-330(Selinexor) chemical structureDC7067

KPT-330(Selinexor)

KPT-330, analog of KPT-185, is an orally bioavailable selective CRM1 inhibitor.IC50 value: Target: CRM1in vitro: As the clinical candidate analog of KPT-185, KPT-330 exhibits similar effects on the viability of T-ALL…

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Verdinexor (KPT-335) chemical structureDC8429

Verdinexor (KPT-335)

Verdinexor(KPT-335) is a novel, orally bioavailable selective inhibitor of nuclear export (SINE), inhibits nuclear export protein Exportin 1(XPO1/CRM1) against canine tumor cell lines; also reduce influenza virus…

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