DC7675BX-471（ZK 811752）
BX471 (ZK-811752) is a potent and selective non-peptide CCR1 antagonist with a Ki of 1 nM, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
View activity & pricesDC Chemicals · Research reagentsDC7675 
DC3154
DC8741
DC7694
DC8281
DC9742
Multiple Sclerosis
6 products · Page 1 of 1
All small molecule research tools
DC7675DC3154Fingolimod HCl（FTY-720）
Fingolimod hydrochloride is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells.
View activity & pricesDC8741Plerixafor octahydrochloride
Plerixafor octahydrochloride is a selective CXCR4 antagonist with an IC50 of 44 nM.
View activity & pricesDC7694BAF312 (Siponimod)
Siponimod (BAF-312) is a potent and selective sphingosine-1-phosphate (S1P) receptor modulator. It is selective for S1P1 and S1P5 receptors over S1P2, S1P3, and S1P4 (EC50s of 0.39, 0.98, >10,000, >1,000, and 750 nM,…
View activity & pricesDC8281Ozanimod (RPC1063)
Ozanimod is a potent and selective S1P1 and S1P5 receptor agonist with EC50s of 410±160 pM and 11±4.3 nM in [35S]-GTPγS binding, respectively.
View activity & pricesDC9742Ponesimod
Ponesimod(ACT-128800) is an orally active, selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator.
View activity & prices