DC Chemicals · Research reagents

Chemotherapeutic Agents

18 products · Page 1 of 1

All small molecule research tools

Carboplatin chemical structureDC9095

Carboplatin

Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of cisplatin and a potent anti-cancer…

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Voreloxin chemical structureDC7530

Voreloxin

Voreloxin is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis.

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Oxaliplatin chemical structureDC5885

Oxaliplatin

Oxaliplatin is a DNA synthesis inhibitor. It causes DNA crosslinking damage, prevents DNA replication and transcription and causes cell death.

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Imisopasem manganese chemical structureDC10406

Imisopasem manganese

M40403 is a small molecule, synthetic manganese containing superoxide dismutase mimetic (SODm) that removes superoxide anions without interfering with other reactive species known to be involved in inflammatory…

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RX-3117 chemical structureDC7762

RX-3117

RX-3117(TV-1360; Fluorocyclopentenylcytosine) is novel a cytidine analog; shows anticancer activity in several cancer cell lines, including gemcitabine-resistant variants.

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Cyclophosphamide chemical structureDC9013

Cyclophosphamide

Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.

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5-Fluorouracil chemical structureDC8944

5-Fluorouracil

5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools.5-Fluorouracil is metabolized to ribonucleotides and…

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Pemetrexed disodium chemical structureDC8149

Pemetrexed disodium

Pemetrexed disodium is a novel antifolate that inhibits the folatedependent enzymes thymidylate synthase, dihydrofolate reductase, and glycinamide ribonucleotide formyltransferase with Kis of 1.3, 7.2, and 65 nM,…

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