DC Chemicals · Research reagents

SGLT

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Canagliflozin chemical structureDC3111

Canagliflozin

Canagliflozin is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively.

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Sotagliflozin (LX-4211) chemical structureDC7921

Sotagliflozin (LX-4211)

LX-4211 is a potent dual SGLT2/1 inhibitor; Antidiabetic agents.IC50 value:Target: SGLT1/2LX4211 enhanced urinary glucose excretion by inhibiting SGLT2-mediated renal glucose reabsorption; markedly and significantly…

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PF-04971729 (Ertugliflozin) chemical structureDC3108

PF-04971729 (Ertugliflozin)

Ertugliflozin (PF-04971729) is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2[1]. A drug for the treatment of type 2…

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