DC5193Roxadustat(FG-4592)
Roxadustat (FG-4592) is an oral hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor developed for the treatment of anemia.
View activity & pricesDC Chemicals · Research reagentsDC5193 
DC9044
DC8447
DC8188
DC10464
DC8166
DC7486
DC8390
HIF/HIF Prolyl-hydroxylase
8 products · Page 1 of 1
All small molecule research tools
DC5193DC90442-Methoxyestradiol
2-Methoxyestradiol is an angiogenesis inhibitor and apoptosis inducer with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules.
View activity & pricesDC8447KC7F2
KC7F2 is a potent HIF-1 pathway inhibitor and that its potential as a cancer therapy agent warrants further study.Target：HIFin vitro: KC7F2 is the second HIF-1α inhibitor. KC7F2 is shown to inhibit the proliferation of…
View activity & pricesDC8188Daprodustat
Daprodustat (GSK1278863) is an orally active hypoxia-inducible factor prolyl hydroxylase inhibitor being developed for the treatment of anemia associated with chronic kidney disease.
View activity & pricesDC10464PT2385
PT-2385 is a selective HIF-2α antagonist with a Ki of less than 50 nM.
View activity & pricesDC8166Molidustat(BAY 85-3934)
Molidustat (BAY 85-3934) is a novel inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) with mean IC50 values of 480 nM for PHD1, 280 nM for PHD2, and 450 nM for PHD3.
View activity & pricesDC7486PX-478 2HCL
PX-478 is an antitumor inhibitor of hypoxia-inducible factor-1α (HIF-1α).
View activity & pricesDC8390Oltipraz
Oltipraz has an inhibitory effect on HIF-1α activation by insulin in a time-dependent manner, completely abrogating HIF-1α induction at ≥10 μM concentrations, the IC50 of Oltipraz for HIF-1α inhibition is 10 μM.
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