DC7060AZD1152
AZD1152 is a pro-drug of Barasertib-hQPA, which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.
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DC7140
DC7466
DC2016
DC7118
DC4125
DC5111
DC7070
DC1029
DC7964
Aurora Kinase
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All small molecule research tools
DC7060DC7140GSK1070916
GSK-1070916 is a potent and selective ATP-competitive inhibitor of aurora B and aurora C with Kis of 0.38 and 1.5 nM, respectively, and is >250- fold selective over Aurora A.
View activity & pricesDC7466MK-5108
MK-5108 inhibits Aurora-A activity in an ATP-competitive manner. MK-5108 shows robust selectivity against the other family kinases Aurora-B (220-fold) and Aurora-C (190-fold) in the biochemical assay. MK-5108 also…
View activity & pricesDC2016MLN8237 (Alisertib)
Alisertib (MLN 8237) is a selective Aurora A inhibitor with an IC50 of 1.2 nM.
View activity & pricesDC7118ENMD-2076
ENMD-2076 is a multi-targeted kinase inhibitor with IC50s of 1.86, 14, 58.2, 15.9, 92.7, 70.8, 56.4 nM for Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα, respectively.
View activity & pricesDC4125PHA-739358 (danusertib)
Description of Danusertib: Danusertib is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity. Aurora kinase inhibitor PHA-739358 binds to and inhibits the Aurora kinases, which may result…
View activity & pricesDC5111PHA-680632
PHA-680632 is an aurora kinase inhibitor with IC50s of 27, 135 and 120 nM for aurora A, B and C, respectively.
View activity & pricesDC7070AT9283
AT9283 is a multitargeted kinase inhibitor which potently inhibits aurora kinase A/B, JAK2/3 (IC50=1.2 nM, 1.1 nM).
View activity & pricesDC1029AZD-1152-HPQA
AZD1152-HQPA is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay, and appr 3700 fold more selective for Aurora B over Aurora A.
View activity & pricesDC7964Aurora A Inhibitor I
Aurora A inhibitor I is a potent and highly selective Aurora A inhibitor with with an IC50 of 3.4 nM.
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