Colon Cancer

9 products · Page 1 of 1

All small molecule research tools

DC7186

LGK-974

LGK974 is a potent and specific Porcupine (PORCN) inhibitor with an IC50 of 0.1 nM.

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DC1030

Regorafenib (BAY73-4506,Fluoro-Sorafenib)

Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively.

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DC7465

MK-2206 2HCl

MK 2206 is an orally active allosteric Akt inhibitor with IC50s of 5, 12 and 65 nM for Akt1, Akt2 and Akt3, respectively.

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DC9770

NCB-0846

NCB-0846 is an orally available TNIK inhibitor with an IC50 of 21 nM.

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DC8247

KNK437

KNK437 is a HSP inhibitor, and inhibits the induction of HSP105, HSP70, and HSP40.

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DC7283

SCH-772984

SCH772984 potently inhibits ERK1 and ERK2 activity with IC50s of 4 and 1 nM, respectively.

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DC8474

Napabucasin (BBI608)

Napabucasin is a STAT3 inhibitor which blocks stem cell activity in cancer cells.

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DC9682

ML-264

ML264 is an antitumor agent that potently and selectively inhibits Krüppel-like factor five (KLF5) expression.

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DC9777

Regorafenib monohydrate（BAY 73-4506）

Regorafenib monohydrate is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.

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