DC1075AZD4547
AZD4547 is a potent inhibitor of the FGFR family with IC50s of 0.2 nM, 2.5 nM, 1.8 nM, and 165 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.
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DC11089
DC7019
DC8280
DC7508
DC5194
DC10068
DC10092
DC10128
DC4157
DC9642
DC10033
DC8418
DC11387
FGFR
15 products · Page 1 of 1
All small molecule research tools
DC1075DC11089TAS-120 (Futibatinib)
TAS-120 is a novel, potent and highly selective FGFR inhibitor, used for antitumor treatment.
View activity & pricesStructure information available on request
DC8330FIIN-2
FIIN-2 is an irreversible inhibitor of FGFR with an IC50 of 3.1, 4.3, 27, and 45 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.
View activity & pricesDC7019LY-2874455
LY2874455 is a pan-FGFR inhibitor with IC50s of 2.8, 2.6, 6.4, 6 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively.
View activity & pricesDC8280BLU-9931
BLU9931 is a potent, selective, and irreversible FGFR4 inhibitor with an IC50 of 3 nM.
View activity & pricesDC7508SU 5402
SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGFRβ, respectively.
View activity & pricesDC5194NVP-BGJ398(Infigratinib)
Infigratinib (BGJ-398) is a potent inhibitor of the FGFR family with IC50s of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.
View activity & pricesDC10068PD166866
PD166866 is a selective FGFR1 tyrosine kinase inhibitor with an IC50 of 52.4 nM.
View activity & pricesDC10092BLU554(Fisogatinib)
BLU-554 is a potent fibroblast growth factor receptor 4 (FGFR4) inhibitor.
View activity & pricesDC10128FGF401( Roblitinib)
FGF-401 is an inhibitor of FGFR4 extracted from patent WO2015059668A1, compound example 83; has an IC50 of 1.9 nM.
View activity & pricesDC4157Dovitinib (TKI258, CHIR258)
Dovitinib is a multi-targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8/9, 10/13/8, 27/210 nM for FLT3, c-Kit, FGFR1/3, VEGFR1/2/3 and PDGFRα/β, respectively.
View activity & pricesDC9642FIIN-3
FIIN-3 is an irreversible inhibitor of FGFR with an IC50 of 13.1, 21, 31.4, and 35.3 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.
View activity & pricesDC10033H3B-6527
H3B-6527 (H3 Biomedicine) is a highly selective FGFR4 inhibitor with potent antitumour activity in FGF19 amplified cell lines and mice.
View activity & pricesDC8418CH5183284 (Debio-1347)
CH5183284 is an orally available and selective FGFR inhibitor with IC50s of 9.3, 7.6, and 22 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.
View activity & pricesDC11387Erdafitinib
Erdafitinib (JNJ-42756493) is a potent and orally available FGFR family inhibitor; inhibits FGFR1/2/3/4 with IC50s of 1.2, 2.5, 3.0 and 5.7 nM, respectively.
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