TAS-120 (Futibatinib) chemical structure
Chemical structureResearch use only
CAT. NO. DC11089Featured

TAS-120 (Futibatinib)

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TotalUS$950
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Product overview

Description & Application

TAS-120 is a novel, potent and highly selective FGFR inhibitor, used for antitumor treatment.

ParameterValue
Chemical Name1-[(3S)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en1-one
CAS No.1448169-71-8
SynonymsFutibatinib;TAS120
FormulaC22H22N6O3
M.Wt418.457
SMILESC(N1CC[C@@H](N2C3C(C(C#CC4=CC(OC)=CC(OC)=C4)=N2)=C(N)N=CN=3)C1)(=O)C=C
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

TAS-120 is a novel, potent and highly selective FGFR inhibitor, used for antitumor treatment.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

TAS-120 (3, 30, 100 mg/kg/day, p.o.) exerts an anti-tumor effect in mice. TAS-120 shows anti-tumor effect by administering at moderate intervals, such as intermittent administration of every other day dosing and 2 times/week, and reducing the sustained elevation and weight suppression blood phosphorus level, and take a antitumor effective as daily administration[1].

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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