DC7246SR3677
SR-3677 is a potent and selective ROCK-II inhibitor with an IC50 of ~3 nM.
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DC7246SR-3677 is a potent and selective ROCK-II inhibitor with an IC50 of ~3 nM.
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DC6902Thiazovivin is a potent ROCK inhibitor, which can protect human embryonic stem cells.
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DC7774Ripasudil (K-115) is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively.
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DC7144GSK429286A is a selective inhibitor of ROCK1 with an IC50 value of 14 nM.
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DC7249GSK269962A is a potent ROCK inhibitor with IC50s of 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively.
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DC9854SAR407899 is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively.
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DC8831RKI-1313 is the negative control for RKI-1447 which is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer
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DC8329SLx-2119 is a selective inhibitor of ROCK2 with an IC50 of 105 nM.
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DC7269RKI-1447 is a potent small molecule inhibitor of ROCK1 and ROCK2 with IC50 values of 14.5 nM and 6.2 nM, respectively.
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DC9614Hydroxyfasudil hydrochloride is a ROCK inhibitor, with IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively.
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DC45762Y-27632 is an ATP-competitive inhibitor of ROCK-I and ROCK-II, with Ki of 220 nM and 300 nM for ROCK-I and ROCK-II, respectively.
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DC72592Zelasudil is a Rho-associated (ROCK) kinase inhibitor. Zelasudil has a ROCK2 binding affinity.
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