26 products · Page 1 of 1
All small molecule research tools
DC1057Fidaxomicin(OPT-80; PAR-101) is a new class of narrow spectrum macrocyclic antibiotic drug; selective eradication of pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria that…
View activity & prices
DC8928Minocycline hydrochloride is a broad-spectrum tetracycline antibiotic, acting by binding to the bacterial 30S ribosomal subunit and inhibiting protein synthesis.
View activity & prices
DC10109Q203 (IAP6) is a midazopyridine amide compound. Q203 is active against Mycobacterium tuberculosis H37Rv with an MIC50 of 2.7 nM in culture broth medium.
View activity & prices
DC8336Tizoxanide is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses.
View activity & prices
DC9723Macozinone is a new drug candicate that inhibits decaprenylphosphoryl-β-d-ribose 2′-oxidase (DprE1), more efficiently than BTZ043target: DprE1In vitro: PBTZ169, inhibit decaprenylphosphoryl-β-d-ribose 2′-oxidase…
View activity & prices
DC9827Epetraborole hydrochloride is a novel leucyl-tRNA synthetase (LeuRS) inhibitor, which inhibits protein synthesis by binding "to the terminal adenosine ribose (A76) of leucyl-tRNA synthetase". It is intended for the…
View activity & prices
DC10441Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases [ESBLs] and KPC) and class C (AmpC) enzymes.Target:…
View activity & prices
DC10612Delpazolid is a novel oxazolidinone antibiotic agent which can inhibit the growth of MSSA and MRSA with a MIC90 of 2 μg/mL for both of them.
View activity & prices
DCAPI1493Dalbavancin is a lipoglycopeptide antibiotic agent that is active against gram-positive pathogens.
View activity & prices
DC41966CSP1 is a potent and selective ComD1 receptor agonist, with an IC50 of 10.3 nM. CSP1 is a major variants of competence-stimulating peptide (CSP), and it can regulate genetic transformation of S. pneumonia by modulating…
View activity & prices
DC7532Walrycin B is a novel antibacterial compound specifically targeting the essential WalR response regulator.Walrycin B is known as an analog of toxoflavin (a phytotoxin from Burkholderia glumae), which has been shown to…
View activity & prices
DC8032Solithromycin is a novel fluoroketolide with improved antimicrobial effectiveness.Solithromycin binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis. The mean 50% inhibitory concentrations…
View activity & prices
DC8809Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
View activity & prices
DC10513AFN-1252(Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibited all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of ≤0.12 μg/ml. IC50…
View activity & prices
DC70368DU011 is a noncanonical anti-infective agent and small-molecule inhibitor of capsule biogenesis, targets MprA (Kd=30 nM), a MarR family transcriptional repressor of multidrug efflux pumps, inhibits capsule expression…
View activity & prices
DC7764Delamanid, a newer mycobacterial cell wall synthesis inhibitor, inhibits the synthesisi of mucolic acids, cruciala component of the cell wall of the Mycobacterium tuberculosis complex.
View activity & prices
DC4143Besifloxacin hydrochloride is a fourth-generation fluoroquinolone antibiotic.
View activity & prices
DC70459GSK 3011724A (DG-167, GSK-3011724A) is a potent, specific inhibitor of β-ketoacyl-ACP synthase (KasA, Kd=9 nM), shows anti-tubercular activity (MIC H37Rv=0.8 uM); shows much weaker apparent dissociation constant for…
View activity & prices
DC4226For the detailed information about the solubility of Moxifloxacin hydrochloride in water, the solubility of Moxifloxacin hydrochloride in DMSO, the solubility of Moxifloxacin hydrochloride in PBS buffer, the animal…
View activity & prices
DC10733Sutezolid (PNU-100480) is an oxazolidinone antimicrobial being developed for the treatment of tuberculosis.Target: AntibacterialSutezolid is a much-awaited drug candidate for treatment of Mycobacterium tuberculosis.…
View activity & prices
DC72952Savirin (S. aureus virulence inhibitor) is a small molecule that targets the agr (accessory gene regulator) quorum sensing system in Staphylococcus aureus (S. aureus). The agr system is a key regulatory pathway that…
View activity & prices
DC8440Erythromycin Cyclocarbonate, derivative of Erythromycin, which is active against Gram-positive and some Gram-negative microorganisms.
View activity & prices
DC11273Murepavadin (POL7080) is a highly potent, specific, macrocycle Pseudomonas antibiotic for the treatment of bacterial infections caused by Pseudomonas aeruginosa. Bacterial Infection Phase 3 Clinical
View activity & prices
DCAPI1325For the detailed information of Rifabutin (Mycobutin), the solubility of Rifabutin (Mycobutin) in water, the solubility of Rifabutin (Mycobutin) in DMSO, the solubility of Rifabutin (Mycobutin) in PBS buffer, the…
View activity & prices
DC28735PK150, an analogue of Sorafenib, shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitive S. aureus…
View activity & prices
DC448173,4,5-Trimethoxybenzaldehyde is an intermediate for the synthesis of various pharmaceuticals, especially for trimethoprim used to treat bacterial infections, including urinary tract pathogens infection.
View activity & prices