DC Chemicals · Research reagents

Microtubule/Tubulin

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All small molecule research tools

ABT-751(E 7010) chemical structureDC7353

ABT-751(E 7010)

ABT-751(E 7010) is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with IC50 of about 1.5 and 3.4 μM in neuroblastoma and non-neuroblastoma cell lines, respectively.

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Ixabepilone chemical structureDCAPI1510

Ixabepilone

Ixabepilone is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and…

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Epothilone B chemical structureDC4198

Epothilone B

Epothilone B is a microtubule stabilizer with a Ki of 0.71μM. It acts by binding to the αβ-tubulin heterodimer subunit which causes decreasing of αβ-tubulin dissociation.

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