DC Chemicals · Research reagents

E3 Ligase Ligand

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Thalidomide-5-OH chemical structureDC41134

Thalidomide-5-OH

Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTACs[1].

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VH032 chemical structureDC11579

VH032

VH-032 (VHL ligand 1) is a VHL ligand for PROTAC and potent, small molecule inhibitor of the VHL/HIF-1α interaction with Kd of 185 nM.

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