DC Chemicals · Research reagents

Elastase

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Sivelestat (sodium salt hydrate) chemical structureDC8592

Sivelestat (sodium salt hydrate)

Sivelestat(ONO5046; LY544349; EI546) is a competitive inhibitor of human neutrophil elastase(IC50 = 44 nM; Ki=200 nM); also inhibited leukocyte elastase obtained from rabbit, rat, hamster and mouse.ONO-5046 did not…

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BAY-8040 (R) chemical structureDC11857

BAY-8040 (R)

Bay-8040 is a potent, selective human neutrophil elastase (HNE) inhibitor with IC50 of 28 nM; displays no significant inhibition toward 68 other pharmacologically relevant targets (>10 uM), and a panel of related…

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