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Kinases & Cell SignalingKinase inhibitors and modulators of intracellular signaling pathways.936 products →Epigenetics & Gene RegulationChromatin, transcription and epigenetic regulation.277 products →DNA Damage, Repair & Cell CycleDNA replication, repair, mitosis and cell-cycle regulation.228 products →Cell Death & AutophagyApoptosis, ferroptosis, necroptosis and autophagy research.117 products →Protein Degradation & ProteostasisPROTACs, molecular glues, ubiquitin systems, chaperones and proteostasis.173 products →Immunology & InflammationInnate and adaptive immunity, inflammatory pathways and immune signaling.297 products →NeuroscienceNeurotransmission, neural targets and neurological research.363 products →GPCRs & Receptor BiologyG-protein-coupled, nuclear and other ligand-binding receptors and their modulators.428 products →Ion Channels & TransportersIon channels, membrane transporters and pumps.196 products →Metabolism & EndocrinologyMetabolic enzymes, lipid and glucose metabolism and hormone signaling.404 products →Cardiovascular & HematologyVascular biology, coagulation, cardiac function, blood-pressure and hematology research.141 products →Anti-infectivesAntibacterial, antiviral, antifungal and antiparasitic research tools.202 products →Cancer ResearchCompounds with documented oncology research applications.530 products →ADCs & BioconjugationADC payloads, linkers, drug-linker conjugates and conjugation reagents.38 products →Probes & Assay ReagentsFluorescent and imaging probes, enzyme substrates and assay reagents.82 products →Natural ProductsNaturally occurring compounds for biological and chemical research.73 products →Cell Biology & Intracellular TransportCytoskeletal dynamics, endocytosis, vesicle trafficking, organelle function and cell differentiation.61 products →
Other Research Tools (75) · Additional reagents, building blocks and specialized research tools.
Natural Products products
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Dacarbazine
CAS 4342-03-4
For the detailed information of Dacarbazine, the solubility of Dacarbazine in water, the solubility of Dacarbazine in DMSO, the solubility of Dacarbazine in PBS buffer, the animal experiment（test） (test) of Dacarbazine, the cell expriment (test) of…
Trigonelline
CAS 535-83-1
Trigonelline, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.
Eupalinolide B
CAS 877822-41-8
Eupalinolide B is a germacrane sesquiterpene isolated from Eupatorium lindleyanum. Eupalinolide B demonstrates potent cytotoxicity against A-549, BGC-823 and HL-60 tumour cell lines[1].
Glabridin
CAS 59870-68-7
Glabridin is a natural isoflavan from Glycyrrhiza glabra, binds to and activates PPARγ, with an EC50 of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic,…
Tretinoin(Retinoic acid）
CAS 302-79-4
Tretinoin(Retinoic acid） is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ…
Oridonin
CAS 28957-04-2
Oridonin, a diterpenoid isolated from Rabdosia rubescens, acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9 μM for AKT1 and AKT2; Oridonin possesses anti-tumor, anti-bacterial and anti-inflammatory effects.
Lycopene
CAS 502-65-8
Lycopene is naturally occurring carotenoids found in tomato, tomato products, and in other red fruits and vegetables; exhibits antioxidant effects.
Miquelianin (Quercetin 3-O-glucuronide)
CAS 22688-79-5
Miquelianin (Quercetin 3-O-glucuronide) is a metabolite of quercetin and a type of natural flavonoid.
Indirubin
CAS 479-41-4
Indirubin(Couroupitine B) is a purple 3,2- bisindole and a stable isomer of indigo isolated from Indigo naturalis (Apiaceae); anti-inflammatory and anticancer activities.IC50 value:Target:in vitro: The activation of EGF receptor, known to be highly expressed…
Eupatilin
CAS 22368-21-4
Eupatilin, a lipophilic flavonoid isolated from Artemisia species, is a PPARα agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities.
Fumagillin
CAS 23110-15-8
Fumagillin(NSC9168) is a complex biomolecule and used as an antimicrobial agent.Target: AntiparasiticFumagillin is an active amebicide and anti-infective isolated from the fungus Aspergillus fumigatus. Fumagillin does exhibit some side effects that have…
Brassinin
CAS 105748-59-2
Brassinin is a phytoalexin found in Chinese cabbage. An effective inhibitor of stage two skin carcinogenesis. Brassinin is an inducer of Phase II enzymes and inhibitor of chemically induced carcinogenesis.
Securinine
CAS 5610-40-2
(-)-Securinine is plant-derived alkaloid and also a GABAA receptor antagonist.
Epiandrosterone
CAS 481-29-8
Epiandrosterone is a steroid hormone with weak androgenic activity. Epiandrosterone is naturally produced by the enzyme 5α-reductase from the adrenal hormone DHEA.
Antibiotic 1037
CAS 606-58-6
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage, with an IC50 of 80 nM. Toyocamycin (Vengicide) induces apoptosis. Toyocamycin (Vengicide) shows no…
Cyclovirobuxin D(Bebuxine)
CAS 860-79-7
Cyclovirobuxine D (CVB-D) is the main active component of the traditional Chinese medicine Buxus microphylla. Cyclovirobuxine D induces autophagy and attenuates the phosphorylation of Akt and mTOR[1]. Cyclovirobuxine D inhibits cell proliferation of gastric…
L-Stepholidine
CAS 16562-13-3
L-Stepholidine (Stepholidine), an alkaloid extract of the Chinese herb Stephania intermedia, is the first compound known to exhibit mixed dopamine D1 receptor agonist/D2 antagonist properties. L-Stepholidine (Stepholidine) has neuroprotective effect and…
5-Hydroxy-1,4-naphthalenedione(Juglone)
CAS 481-39-0
Juglone is a yellow pigment found in black walnut (Juglans regia). Juglone also shows antimicrobial activity[1].
Rebaudioside C
CAS 63550-99-2
Rebaudioside C(Dulcoside B) is used as natural sweeteners to diabetics and others on carbohydrate-controlled diets.
Dioscin
CAS 19057-60-4
Dioscin(CCRIS 4123; Collettiside III) is a natural steroid saponin derived from several plants, showing potent anti-cancer effect against a variety of tumor cell lines.
Deguelin
CAS 522-17-8
Deguelin, a naturally occurring rotenoid, is known to be an Akt inhibitor and to have an anti-tumor effect on several cancers; decrease levels of phosphorylated Akt. in vitro: Deguelin in a dose and time dependent manner inhibited the growth of MDA-MB-231,…
Cytochalasin H
CAS 53760-19-3
Cytochalasin H is a potent inhibitor of actin incorporation into filaments,a cell-permeable fungal toxin used in actin polymerization studies and cytological research. Cytochalasin H suppresses the production of reactive oxygen species by stimulated human…
Magnolol
CAS 528-43-8
Magnolol, a natural lignan isolated from the stem bark of Magnolia officinalis, is a dual agonist of both RXRα and PPARγ, with EC50 values of 10.4 µM and 17.7 µM, respectively.
Prodigiosin
CAS 82-89-3
Prodigiosin (Prodigiosine) is a secondary metabolite of Symbiotic bacteria, with anti-fungal and anti-cancer activity[1][2].
Bufalin
CAS 465-21-4
Bufalin a major digoxin-like immunoreactive component of the Chinese medicine Chan Su; has been shown to exert a potential for anticancer activity against various human cancer cell lines in vitro.
Sudan IV；Solvent Red 24
CAS 85-83-6
For the detailed information of Sudan IV；Solvent Red 24, the solubility of Sudan IV；Solvent Red 24 in water, the solubility of Sudan IV；Solvent Red 24 in DMSO, the solubility of Sudan IV；Solvent Red 24 in PBS buffer, the animal experiment（test） (test) of…
Ursocholic acid
CAS 2955-27-3
Ursocholic acid, a bile acid found predominantly in bile of mammals, is an inhibitor of 7α-hydroxysteroid dehydrogenase and hepatocyte nuclear factor 1α.
Marmesin
CAS 13849-08-6
S-(+)-Marmesin is a natural coumarin, exhibiting COX-2/5-LOX dual inhibitory activity.
DEOXYNIVALENOL
CAS 51481-10-8
Deoxynivalenol, a mycotoxin of the trichothecenes family, crosses the intestinal mucosa by a paracellular pathway through the tight junctions. The Deoxynivalenol transport is not affected by P-glycoprotein (PgP) or multidrug resistance-associated proteins…
Alliin
CAS 556-27-4
For the detailed information of Alliin, the solubility of Alliin in water, the solubility of Alliin in DMSO, the solubility of Alliin in PBS buffer, the animal experiment（test） (test) of Alliin, the cell expriment (test) of Alliin, the in vivo, in vitro and…
Mannitol
CAS 87-78-5
For the detailed information of Mannitol, the solubility of Mannitol in water, the solubility of Mannitol in DMSO, the solubility of Mannitol in PBS buffer, the animal experiment（test） (test) of Mannitol, the cell expriment (test) of Mannitol, the in vivo, in…
didymin
CAS 14259-47-3
For the detailed information about the solubility of didymin in water, the solubility of didymin in DMSO, the solubility of didymin in PBS buffer, the animal experiment（test） of didymin,the in vivo,in vitro and clinical trial test of didymin,the cell…
Harmine
CAS 442-51-3
For the detailed information of Harmine , the solubility of Harmine in water, the solubility of Harmine in DMSO, the solubility of Harmine in PBS buffer, the animal experiment（test） (test) of Harmine , the cell expriment (test) of Harmine , the in vivo, in…
Chlorotoxin
CAS 163515-35-3
Chlorotoxin is a 36 amino-acid peptide from the venom of the Israeli scorpion Leiurus quinquestriatus with anticancer activity. Chlorotoxin is a chloride channel blocker.
Echinocystic acid
CAS 510-30-5
Echinocystic acid a pentacyclic triterpene isolated from the fruits of Gleditsia sinensis Lam, has potent antioxidant, anti-inflammatory and anti-tumor properties. In vitro: Echinocystic acid (EA) inhibit the formation of osteoclast. EA inhibit RANKL-induced…
Ingenol 3-angelate
CAS 75567-37-2
Ingenol 3-Angelate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
Vinblastine sulfate
CAS 143-67-9
For the detailed information of Vinblastine sulfate, the solubility of Vinblastine sulfate in water, the solubility of Vinblastine sulfate in DMSO, the solubility of Vinblastine sulfate in PBS buffer, the animal experiment（test） (test) of Vinblastine sulfate,…
Colchicine
CAS 64-86-8
Colchicine is a potent therapeutic tool against COVID-19. Colchicine is a tricyclic alkaloid that is extracted from the plant Colchicum autumnale. Colchicine acts as a potent inhibitor of tubulin polymerization.
7-Methoxycoumarin
CAS 531-59-9
For the detailed information of 7-Methoxycoumarin, the solubility of 7-Methoxycoumarin in water, the solubility of 7-Methoxycoumarin in DMSO, the solubility of 7-Methoxycoumarin in PBS buffer, the animal experiment（test） (test) of 7-Methoxycoumarin, the cell…
Hypaconitine
CAS 6900-87-4
For the detailed information of Hypaconitine, the solubility of Hypaconitine in water, the solubility of Hypaconitine in DMSO, the solubility of Hypaconitine in PBS buffer, the animal experiment（test） (test) of Hypaconitine, the cell expriment (test) of…
Sanguinarine
CAS 2447-54-3
For the detailed information of Sanguinarine, the solubility of Sanguinarine in water, the solubility of Sanguinarine in DMSO, the solubility of Sanguinarine in PBS buffer, the animal experiment（test） (test) of Sanguinarine, the cell expriment (test) of…
Amentoflavone
CAS 1617-53-4
For the detailed information of Amentoflavone, the solubility of Amentoflavone in water, the solubility of Amentoflavone in DMSO, the solubility of Amentoflavone in PBS buffer, the animal experiment（test） (test) of Amentoflavone, the cell expriment (test) of…
Hypocrellin B
CAS 123940-54-5
Hypocrellin B, a pigment isolated from the fungi Hypocrella bambusae and Shiraia bambusicola, is an apoptosis inducer. Hypocrellin B can be used as a photosensitizer for photodynamic therapy of cancer. Hypocrellin B also has antimicrobial and antileishmanial…
Homoorientin
CAS 4261-42-1
For the detailed information about the solubility of Homoorientin in water, the solubility of Homoorientin in DMSO, the solubility of Homoorientin in PBS buffer, the animal experiment（test） of Homoorientin,the in vivo,in vitro and clinical trial test of…
6-Shogaol
CAS 555-66-8
6-shogaol, an active compound isolated from Ginger (Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
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