Cell Biology & Intracellular Transport

Paprotrain

CAS 57046-73-8

Reversible, non-ATP competitive inhibitor of mitotic kinesin-like protein 2 (MKLP-2)

Bexin-1

CAS 1172933-44-6

Bexin-1 is a specific inhibitor that targets Munc13-4, a protein critical for regulated exocytosis, particularly in secretory cells such as immune cells (e.g., cytotoxic T lymphocytes, mast cells) and neuroendocrine cells. Munc13-4 plays a key role in vesicle…

Remodelin

CAS 949912-58-7

Remodelin is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.Remodelin can improve nuclear architecture, chromatin organization, and fitness of both human lamin A/C-depleted cells and HGPS-derived patient cells, and decrease…

Remodelin (hydrobromide)

CAS 1622921-15-6

Remodelin HBr salt is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.Remodelin can improve nuclear architecture, chromatin organization, and fitness of both human lamin A/C-depleted cells and HGPS-derived patient cells, and…

1-EBIO

CAS 10045-45-1

1-EBIO is an Epithelial KCa channel activator. Promotes ESC differentiation into cardiomyocytes.

Thymosin beta 4

CAS 77591-33-4

Thymosin beta 4 is a potent regulator of actin polymerization in living cells. Sequence:…

Auristatin E

CAS 160800-57-7

Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates.

Kartogenin (KGN)

CAS 4727-31-5

Kartogenin is an inducer of differentiation of human mesenchymal stem cells into chondrocytes.

MitoBloCK-11

CAS 413606-16-3

MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in…

NNMTi

CAS 42464-96-0

NNMTi is a potent nicotinamide N-methyltransferase (NNMT) inhibitor (IC50=1.2 μM) and selectively binds to the NNMT substrate-binding site residues[1]. NNMTi promotes myoblast differentiation in vitro and enhances fusion and regenerative capacity of muscle…

NACE2i

NACE2i is a cell permeable, specific and selective peptide inhibitor of nuclear ACE2, inhibits binding between IMP1α and ACE2 and SARS-CoV-2 viral replication. NACE2i specifically targets nuclear ACE2 and not other nuclear proteins targeted by the importin…

ML-098

CAS 878978-76-8

ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 with an EC50 of 77.6 nM.

ES9-17

CAS 55854-43-8

ES9-17 is a CME inhibitor a, ES9-17 inhibited recruitment of the plasma membrane-localized BRI1-GFP to the BFA body. Samples were pretreated with 50 µM CHX for 1 h and treated with either DMSO (indicated as Ø) or ES9-17 (30 µM) for 30 min, followed by a…