DC Chemicals · Research reagents

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1099 products · Page 20 of 23

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SW203668 chemical structureDC34176

SW203668

SW203668 is a potent, tumor-specific inhibitor of stearoyl CoA desaturase (SCD) with better bioavailability than SW208108.

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ALS-I chemical structureDC46349

ALS-I

ALS-I, an acid-Liable surfactant, is adopted for in-solution enzymatic digestions, can help to solubilize hydrophobic proteins. ALS-I is significantly enhanced peptide recovery for mass spectrometry (MS) mapping in the…

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KM822 chemical structureDC60622

KM822

KM822 is avselective, noncompetitive modulator of human dopamine transporter (DAT) with IC50 3.7 μM, which shows 30 and 50 folds higher than for human norepinephrine transporter (hNET) and human serotonin transporter…

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Chloroquine chemical structureDC37947

Chloroquine

Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require…

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Azathioprine (Azasan, Imuran) chemical structureDCAPI1182

Azathioprine (Azasan, Imuran)

For the detailed information of Azathioprine (Azasan, Imuran), the solubility of Azathioprine (Azasan, Imuran) in water, the solubility of Azathioprine (Azasan, Imuran) in DMSO, the solubility of Azathioprine (Azasan,…

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Orlistat (Alli, Xenical) chemical structureDCAPI1397

Orlistat (Alli, Xenical)

For the detailed information of Orlistat (Alli, Xenical), the solubility of Orlistat (Alli, Xenical) in water, the solubility of Orlistat (Alli, Xenical) in DMSO, the solubility of Orlistat (Alli, Xenical) in PBS…

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Amisulpride chemical structureDC31537

Amisulpride

Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. In Italy, it is also used as a treatment for dysthymia. It was introduced by Sanofi-Aventis…

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Trpm2 Inhibitor A23 chemical structureDCC5248

Trpm2 Inhibitor A23

Novel selective inhibitor of the transient receptor potential melastatin 2 (TRPM2) channel, exhibiting TRPM2 selectivity over TRPM8 and TRPV1 channels as well as phospholipase A2 and showing neuroprotective activity in…

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Trilostane(Win 24540; Modrastane) chemical structureDC8629

Trilostane(Win 24540; Modrastane)

Trilostane(Win 24540; Modrastane) is an inhibitor of 3 β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome.Trilostane is an inhibitor of 3 β-hydroxysteroid dehydrogenase (3-β-HSD or delta 5-delta…

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YTHDC1 inhibitor 40 (compound 40) chemical structureDC60707

YTHDC1 inhibitor 40 (compound 40)

YTHDC1 inhibitor 40 is a potent, selective m6A reader YTHDC1 inhibitor with ITC Kd of 49 nM, HTRF IC50 of 0.35 uM. Compound 40 shows antiproliferative activity against the acute myeloid leukemia (AML) cell lines THP-1,…

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DOCK5-IN-C21 chemical structureDC34489

DOCK5-IN-C21

DOCK5-IN-C21 functions as an allosteric inhibitor targeting the guanine nucleotide exchange factor DOCK5, effectively modulating its activity through a non-competitive mechanism.

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Idoxuridine chemical structureDC31184

Idoxuridine

Idoxuridine is an anti-herpesvirus antiviral and anticancer drug. It is a nucleoside analogue, a modified form of deoxyuridine, similar enough to be incorporated into viral DNA replication, but the iodine atom added to…

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Fluorocholine chloride chemical structureDC67510

Fluorocholine chloride

Fluorocholine chloride serves as a versatile biochemical tool for life science investigations, functioning both as an organic compound and biological marker in various research applications.

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SNC-80 chemical structureDC22902

SNC-80

SNC80 (NIH 10815) is a potent, highly selective and non-peptide δ-opioid receptor agonist with a Ki of 1.78 nM and an IC50 of 2.73 nM. SNC80 also selectively activates μ-δ heteromer in HEK293 cells with an EC50 of 52.8…

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LM10 chemical structureDC48542

LM10

LM10 is a potent inhibitor of tryptophan 2,3-dioxygenase (TDO). Tryptophan 2,3-dioxygenase (TDO) is an unrelated hepatic enzyme that also degrades tryptophan along the kynurenine pathway. LM10 has the potential for the…

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PAA-38 HCl chemical structureDC68137

PAA-38 HCl

PAA-38 is a highly potent selective inhibitor targeting bacterial prolyl-tRNA synthetase (ProRS). PAA-38 againsts Pseudomonas aeruginosa ProRS (PaProRS) with a Kd value of 0.399 nM and an IC50 value of 4.97 nM. PAA-38…

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Hydroxyurea (Cytodrox) chemical structureDCAPI1045

Hydroxyurea (Cytodrox)

For the detailed information of Hydroxyurea (Cytodrox), the solubility of Hydroxyurea (Cytodrox) in water, the solubility of Hydroxyurea (Cytodrox) in DMSO, the solubility of Hydroxyurea (Cytodrox) in PBS buffer, the…

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Mifepristone (RU486) chemical structureDC31256

Mifepristone (RU486)

Mifepristone (RU-486) is a potent steroidal antagonist exhibiting subnanomolar affinity for progesterone receptors (PR IC₅₀ = 0.2 nM) and nanomolar activity against glucocorticoid receptors (GR IC₅₀ = 2.6 nM). This…

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Leuprorelin chemical structureDC22504

Leuprorelin

Leuprolide is an agonist at pituitary GnRH receptors. Target: GnRH receptorLeuprorelin is a gonadotrophin-releasing hormone (GnRH) analogue used to treat a wide range of sex hormone-related disorders including advanced…

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Semax chemical structureDC26045

Semax

Semax is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) (4-10) that has neuroprotective, analgesic, and anxiolytic properties.In vivo, semax (0.3 mg/kg) reduces cortical nitric oxide (NO) production…

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Elacridar hydrochloride chemical structureDC22621

Elacridar hydrochloride

Elacridar Hcl (GF120918; GW0918) is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of…

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Lorcaserin chemical structureDC1011

Lorcaserin

LLorcaserin (APD-356)is a weight-loss drug developed by Arena Pharmaceuticals. It has serotonergic properties and acts as an anorectic

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BPH-1358 chemical structureDC53057

BPH-1358

BPH-1358 (NSC50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor with IC50s of 1.8 μM and 110 nM, respectively, and is active against S. aureus in vitro…

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Pimecrolimus chemical structureDC8243

Pimecrolimus

Pimecrolimus is an immunophilin ligand, which binds specifically to the cytosolic receptor, immunophilin macrophilin-12.Pimecrolimus blocks T-lymphocyte activation pathway by inhibiting calcineurin function [1].…

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J-147 chemical structureDC7435

J-147

J-147 is a broad spectrum neuroprotective phenyl hydrazide compound(EC50=60-115 nM) with significant neurotrophic properties related to the induction of brain-derived neurotrophic factor (BDNF).IC50 value: 60-115 nM in…

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Protease K chemical structureDC40111

Protease K

Protease K is a nonspecific serine protease that is useful for general digestion of proteins. Protease K is active in the presence of SDS or urea and over a wide range of pH (4-12), salt concentrations, and temperatures.

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MLS 0263839 chemical structureDC21329

MLS 0263839

MLS 0263839 is a potent, specific inhibitor of the phosphatase PHOSPHO1 with IC50 of 0.14 uM, shows minimal cross-inhibition of TNAP and no inhibition of ENPP1 activity; suppresses vascular smooth muscle cell…

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AC-263093 chemical structureDC12577

AC-263093

AC-263093 (AC263093) is a potent, functionally selective neuropeptide FF receptor type 2 (NPFFR2) agonist with pKi of 6.9; shows equal affinity for NPFFR1 and NPFFR2, and functionally inactivated NPFFR1; attenuates…

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